Tag Archives: prevention

Dr. M’s SPA Newsletter Audiocast Volume 11 Issues 43 and 45, Covid Updates 46 and 47

Coronavirus Updates #46 and 47 – Listen to the latest data driven perspectives on the pandemic and soon to be endemic COVID world. Vaccines, boosters, prevention and what is happening now are covered. For the written versions please visit: https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter

Best, Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 11 Issues 40 and 42

Audiocast #40 – Epigenetics

Humans, like most organisms on earth, grow and maintain their biological systems through a complex interplay between the environment and their genes. Epigenetics is the study of the ability of environmental signals to silence or activate these genes, thus effecting cellular function and species survival. I was once given an analogy, by Dr. Randy Jirtle, that your genes are like a computer hard drive. They do nothing until the software inputs change activity. The environmental signals like food, chemicals, stress and much more are the putative software inputs for us. Good lifestyle inputs have been epidemiologically proven to reduce disease risk.

Audiocast #42 – Stress, Psychiatry and the Intestinal Microbiome

Humans develop disease from many different routes including toxic exposures, genetics, poor nutrition, injury, microbial exposures and much more. One of the biggest risk factors for the development of disease is mental stress. Specifically, chronic stress of the psyche is traumatic to the cellular machinery of the body like the protective telomere tails of DNA strands or the functioning intestinal microbiome.
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #7 – Dr. William Parker, The “Macrobiome” and Human Health

Dr. William Parker, Associate Professor of Surgery and Global Health at Duke University, will discuss the biome depletion theory and how our cleanliness is disrupting normal immune function. These processes can have profound downstream effects on maternal and child health. From the Duke Medical School: What is widely known as the “hygiene hypothesis” is more appropriately described as the biota alteration or biome depletion theory: Changes in symbiont composition in the ecosystem of the human body in Western culture has led to immune dysfunction and subsequent disease. We are working on several aspects of this theory. Our earlier studies probe the immunological differences between laboratory-raised and wild-raised animals as a means of assessing differences between humans with and without Western culture, respectively. Other studies probe the role of biome enrichment, in particular the addition of helminths, in the treatment of disease. Studies are ongoing in both humans and in animals, with particular attention to the role of biome depletion in cognitive dysfunction.

We discuss the future of human health with a specific focus on our macrobiome friends, parasites, with whom we have co evolved. They are now missing and we are not better off because of it.

 

Please enjoy my conversation with Dr. William Parker,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 11 Issues 39 and 41, Covid Updates 44 and 45

Coronavirus Updates #44 and 45 – Listen to the latest data driven perspectives on the pandemic. Vaccine boosters, MIS and what is happening now are covered. For the written versions please visit: https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter

 

Best,

Dr. M

Women and Children First Interview with Dr. Paul Smolen

 

Paul Smolen is a teacher, a thinker and pediatric pearl generator. I sat down with Docsmo for a wonderful conversation about his lengthy and thoughtful career. He discusses his podcast, learning while on the job and what made it all work. He leaves us with his 10 favorite pediatric parenting pearls. I know that you will find his wisdom most useful. Please enjoy my conversation with Dr. Paul Smolen, aka Docsmo.

 

Dr. M

 

Dr. M’s SPA Newsletter Volume 11 Issue 30

Dental Care – Why is it so important?
We have intermittently discussed dental care over the last 11 years with regard to oral health as well as systemic health. There was an excellent podcast between Dr. Peter Attia and Dr. Patricia Corby two weeks ago looking at all things oral health. I am going to distill the 2 hour podcast down into a manageable audio recording of the newsletter with some more information on dental anthropology and the oral microbiome.
Dr. Corby is an oral health researcher from Penn Dental Medicine in Pennsylvania and she is a wealth of research information in the oral space. Read more here – https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter/973-volume-11-letter-30
Have a great day and hug your kids,
Dr. M

Dr. M’s SPA Newsletter Volume 11 Issue 29 Covid Update #39

Coronavirus Update #39 Quick hits
1) Repeat with new information as an important follow up on MIS-C, multi inflammatory syndrome – c., from 2 weeks ago. Remember that in children, MIS-c is associated with poor intestinal function from a microbiome perspective coupled to genetic weaknesses in immune suppression of chemokine CXCL9 post inflammation. Research from the lab of Dr. Alessio Fasano has shown direct evidence of intestinal permeability in children with multi inflammatory syndrome – c:
The authors found that children, unlike adults, the SARS2 virus decides to take up residence in the intestines and replicate there. The virus can be found in the child’s stool via testing. This is a unique finding to children as the intestine is not known to be a harboring site for the virus in adults. The expert researcher on this paper, Dr. Fasano, has extensive knowledge of the function of the intestinal mucosal lining and the fact that the cells are held together by tight junctions made up of different proteins forming a semi impermeable membrane…….
Read more at https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter
Have a great day,
Dr. M