Tag Archives: prevention

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 36

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Section I

Literature Review

1) Long Covid in children – the symptoms are getting more clarity in who has what . From JAMA: 898 school-age children (751 with previous SARS-CoV-2 infection and 147 without) and 4469 adolescents (3109 infected and 1360 uninfected) were included in the analysis. The time between infection and symptom analysis was 1.5 years. In models adjusted for sex and race and ethnicity, 14 symptoms in both school-age children and adolescents were more common in those with SARS-CoV-2 infection history compared with those without infection history, with 4 additional symptoms in school-age children only and 3 in adolescents only. These symptoms affected almost every organ system. The cumulative data shows us that neurocognitive (Headache, attention concerns, sleep dysregulation), pain, and gastrointestinal symptoms in school-age children were common, but changed to loss of smell and/or taste, body aches and pain, focus struggles and fatigue related symptoms in adolescents. (Gross et. al. 2024) Age has a huge effect on these outcomes as the older population has more frequent and problematical disease findings. Mood disorder is highly associated with worsened findings. I suspect from the historical data set over the last four years that children with chronic mental stress, poor quality diets, sleep issues, and poor activity levels at baseline have worsened acute and long term prognosis.

Plus a section on a book review for Change Your Genes, Change Your Life.

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #78 – Elisa Song MD – Healthy Kids Happy Kids

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This week I sit down with Dr. Elisa Song to discuss her new book, Healthy Kids, Happy Kids. Dr. Song is a graduate of Stanford University with a degree in political Science. She then attended New York University for her medical degree and finally a stop at the University of California San Francisco for pediatric residency training. In her own words, Dr. Song is a holistic pediatrician. She founded Whole Family Wellness, an integrative pediatric practice in Belmont, CA – one of the first and most highly regarded holistic pediatric practices in the country. She created Healthy Kids Happy Kids – dedicated to empowering parents to take charge of their kids’ health … naturally! She lectures around the world for the Center for Education and Development in Clinical Homeopathy (CEDH), Academy for Pain Research, Institute for Functional Medicine, and Holistic Pediatric Association, A4M among others. In this interview we look at health through a prevention first lens with a deep look at the intestinal microbiome and nutrition. Dr. Song’s immense fund of knowledge is on full display in her book and this interview.

Please enjoy my conversation with Dr. Elisa Song,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 33

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Sleep Part IV

Continuing the sleep education from a few weeks ago.

Sleep is a most special event that we all need to continue to focus heavily on in order to live a healthy and long life. It may be the single most important event that we do daily.

Here are a few more quick hits on sleep from the Matthew Walker’s Book and other publications.

1) Aim for a minimum of 7 hours nightly to maintain adequate memory consolidation, immune health and emotional regulation. Young children and teens need 8-14 hours depending on age.

2) Do not eat close to bedtime. Stop eating three hours before you plan to go to sleep. Avoid rapidly digesting refined carbohydrates as they turn into energy quickly raising core temperature which makes it harder to fall asleep as we need our body temperature to drop 3 to 4 degrees F at night to fall asleep. Heavy protein meals at night are not a great idea. Eat the heavier proteins early (before 6 pm) if at all in the evening….plus a section on summer Covid surge.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 32

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Sleep Part III

Finally, the other elephant in the room related to sleep is STRESS. Stress alters the function of the hormone cortisol and can significantly alter night sleep function. There are three major chemicals that affect sleep: cortisol, adenosine and melatonin.

In normal conditions, adenosine rises during the day making you sleepy, cortisol hits its low point at night and melatonin rises as the sun goes down. This combination puts pressure on you to feel sleepy and want to go to bed. Unfortunately, modern life has made many of us feel stressed and sympathetically fired up which affects cortisol function. Instead of being at its nadir at night, the stress response causes cortisol to rise at inappropriate times disrupting sleep onset and maintenance. Couple this stress with facebook addiction and screen induced melatonin suppression and you have a recipe for insomnia and disrupted sleep. (Hanson et. al. 2010)….Plus, a section on cellphones and driver knowledge.

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #77 – Colleen Cutcliffe, PhD – Microbes and Health

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This weeks guest is Dr. Colleen Cutcliffe.

Dr. Colleen Cutcliffe is a researcher and a thinker with persistence. Throughout history, these are the human qualities that lead people to develop amazing products and lead projects for the world to benefit from. Her story is one of discovery, passion and caring.

Dr. Cutcliffe holds a Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and a B.A. in Biochemistry from Wellesley College. Her scientific background is complemented by her experience in managing both research and operations teams in the biotech sector. Before founding Pendulum Therapeutics, she held senior positions at Pacific Biosciences and Elan Pharmaceuticals, where she was instrumental in developing various technological platforms. She is the co-founder and CEO of Pendulum Therapeutics, a biotechnology company focused on developing innovative solutions to improve gut health through microbiome-based interventions. With over 20 years of experience in the biotechnology industry, Dr. Cutcliffe has become a recognized leader in microbiome science, applying her expertise to bridge the gap between cutting-edge research and practical, consumer-facing health solutions. At Pendulum Therapeutics, Dr. Cutcliffe has led the development of novel probiotic formulations specifically designed to address metabolic diseases like type 2 diabetes. Her work has been pivotal in the growing recognition of the microbiome’s role in human health, pushing forward the concept of targeted probiotics as a potential therapeutic option. Under her leadership, Pendulum Therapeutics has gained recognition for its scientific rigor and innovative approaches to personalized nutrition.

Today, we discuss the story of her discovery and the fact that her work is the beginning of a hopeful wave of change for humans through gut microbiome manipulation. Dr. Cutcliffe helps us understand the basics of the microbiome, what helps it stay balanced and conversely, what upsets it. How does it support our metabolism and health in general. The main thrust of her work comes into the spotlight with Akkermansia mucinophilia, a keystone species for positive health.

Please Enjoy my conversation with Dr. Cutcliffe,

Dr. M

Dr. M’s SPA Audiocast Newsletter Volume 14 Issue 28

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Klotho Part II

Last week we discussed Klotho as a protein that has pleotrophic effects in the body as it relates to cellular aging. This week let us focus specifically on the brain. What are the effects of klotho as it relates to cognition and function over time? Klotho has neuroprotective effects based on studies that show that better cognitive performance in translational models over time occur with the injections of klotho. Klotho is also shown to have neuroprotective effects if naturally elevated, i.e. individuals with host genetics that promote more klotho production over time without being taken or given.

The pivitol research occurred in 2015 in a mouse model of Alzheimers Disease (AD) where Dr. Dena Dubal and colleagues looked at two groups of intervention mice with and without higher levels of Klotho. and a literature review on micro plastics and screentime.

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #75 – Jeff Kessler, FACHE – Allergies and Therapy

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Jeff Kessler, FACHE

Allergy Choices

This week I sit down with Jeff Kessler to discuss allergies and sublingual immune therapy.

Jeff Kessler is a business leader and a thought leader in the allergy therapy space. His relevant backstory goes back to 1999 when he had the fortunate opportunity to work on a project to select and implement an Electronic Medical Record system for the Allergy Associates of La Crosse (AAOL) clinic in La Crosse WI. Fortuitously for his daughter who at the time suffered profoundly with allergies, asthma and eczema, this opportunity presented a new course of therapy that would eventually be taken for the entire family leading to allergic disease modification. Enthralled with the therapy and company, Jeff dedicated his career in the healthcare industry from that point on to the allergy treatment approach that he witnessed change thousands of lives including his families. The growing AAOL organization became linked to Allergychoices, an education company dedicated to teaching healthcare providers around the U.S. on the protocol (La Crosse Method – LCM) that had been perfected since 1970. Jeff has served as President of Allergychoices since its formation and its services have grown to help providers deliver immunotherapy using the LCM to their patients directly at the primary care level. Bringing together AAOL, the most advanced allergy immunotherapy clinic in the U.S. and Allergychoices, capable of delivering the benefits of disease modifying allergy immunotherapy to anyone, anywhere, the distinctive competencies of these companies continue to help hundreds of thousands of allergy sufferers of all types, including foods.

Jeff earned a bachelors in science from the University of Wisconsin LaCrosse before he received his MBA in Strategic Planning from University of Minnesota’s Carlson School of Management in 1987.

Please enjoy my conversation with Jeff Kessler,

Dr. M

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