Tag Archives: diet

Dr. M’s SPA Audiocast Newsletter Volume 14 Issue 28

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Klotho Part II

Last week we discussed Klotho as a protein that has pleotrophic effects in the body as it relates to cellular aging. This week let us focus specifically on the brain. What are the effects of klotho as it relates to cognition and function over time? Klotho has neuroprotective effects based on studies that show that better cognitive performance in translational models over time occur with the injections of klotho. Klotho is also shown to have neuroprotective effects if naturally elevated, i.e. individuals with host genetics that promote more klotho production over time without being taken or given.

The pivitol research occurred in 2015 in a mouse model of Alzheimers Disease (AD) where Dr. Dena Dubal and colleagues looked at two groups of intervention mice with and without higher levels of Klotho. and a literature review on micro plastics and screentime.

Enjoy,

Dr. M

Dr. M’s SPA Audiocast Newsletter Volume 14 Issue 27

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Klotho Part I
Ok, it is time for a potential log step shift in the human understanding of neurological decline with age starting from birth.
Enter the peptide, (C)Klotho, named after the greek goddess of fate who spins the thread of life for all. The Klotho protein was discovered by researchers looking at mice that aged faster than the general mouse population. These mice were noted to have a shortened lifespan, stunted growth, renal disease, blood vessel calcification, cardiac hypertrophy, hypertension, pulmonary disease, cognitive impairment, multi-organ atrophy and fibrosis. (Prud’homme et. al. 2022) When they looked closer, these mice were found to have hypoactive klotho proteins leading to an explosion of research over the past two decades to understand why. The next question was, could the hyperactive state provide an anti aging effect?
The answer was a resounding yes!
and a discussion on fast food.
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #71 – Steve Hodges, M.D., Ph.D. – Bedwetting and Constipation

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Enuresis, Encopresis and Constipation
This week I sit down with Dr. Steve Hodges to discuss bedwetting, constipation and more.
Dr. Steve Hodges is a Urological surgeon and expert in the field of enuresis, encopresis and child urological health. He received his BA in classical and ancient studies from Duke University before completing medical school and residency at Wake Forest University in North Carolina. He completed further Pediatric fellowships in Urology at the University of San Diego and again at Wake Forest. From there his career is one of exploration, questioning and seeking new answers to old questions. He has authored multiple books including It’s No Accident, Emma and the E Club: An Epic Episode About Eliminating Enuresis and Encopresis, and the MOP book anthology. He is widely published in top Urological Journals.
Today we sit down to dissect the issues of enuresis(Bedwetting), encopresis (self stooling) and chronic constipation. The exploration is exactly what we need, root cause analysis and treatments based on the reasons not the symptoms.
Please enjoy my conversation with Steve Hodges,
Dr. M

Dr. M’s Women and Children First Podcast #54 – Doug Thompson, DDS – Teeth and Systemic Health

 

 

 

 

 

 

 

 

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Today’s guest is Dr. Doug Thompson,  a 27 year veteran of dentistry since he graduated from the University of Michigan School of Dentistry in 1996. Dr. Thompson is a teacher, researcher and trail blazer in the field of modern dentistry. Today we travel down paths that lead to explanations as to why oral health is so important to systemic and truly whole human health. We look back in time and follow a timeline to the present-day research that says that we have scientific knowledge through laboratory study that the oral microbiome, the bacteria that reside with the oral cavity, as well as the oral system’s function has far reaching effects on the heart, the intestines, pregnancy and general metabolic health. Over the decades, Dr. Thompson realized that the science needed a portal to the masses and other dental professionals. Usher in the project called the Wellness Dentistry network circa 2015 which is an internet-based community of dentists with a keen awareness of how oral conditions affect whole-body health. It is a forum for Dr. Thompson and colleagues to use research to develop advanced practice ideas to thwart systemic health concerns that may arise from oral health dysfunction. On his website, Integrative Oral Medicine, Dr. Thompson states that he believes in an interdisciplinary treatment model that coordinates dental care with other medical practitioners for total body health care for his patients. He employs advanced DNA bacterial testing methods and other leading-edge dental science to enable early risk assessment and personalized treatment planning. To me this remains the future of all healthcare disciplines, collaboration, cooperation and patient centered. Let us dive into the oral cavity with Doug Thompson.
Enjoy,
Dr. M

 

Dr. M’s Women and Children First Podcast #53 – Peter Ungar, PhD – Teeth and History

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

This weeks guest is Dr. Peter Ungar. Dr. Ungar serves as Distinguished Professor of Anthropology and Director of the Environmental Dynamics PhD Program at the University of Arkansas. He received his PhD in Anthropological Sciences from Stony Brook University and taught Gross Anatomy in the medical schools at Johns Hopkins and Duke before joining the University of Arkansas faculty in 1995. He is an Honorary Research Fellow of the Center for the Exploration of the Deep Human Journey at the University of the Witwatersrand in Johannesburg, South Africa.
Ungar has written or coauthored more than 200 scientific works on ecology and evolution for journals like Science, Nature, Proceedings of the National Academy of Sciences, Scientific American, and more. His work has focused on teeth, food choices and feeding in living primates, and the role of diet and environmental change in the evolution of human ancestors and other fossil species.
We dive into the world of teeth, evolution and out current state of existence in modern society. Are our teeth matched for this environment?
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 30

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Asthma, Allergies and Nutrition – The Story
Here is a long form look at asthma and allergies as I am preparing a lecture on asthma and allergies for a conference in October. I will break it up into a few parts for your consumption.
  • Asthma is now well known to be an inflammatory disease based on the response to anti-inflammatory medications and pathophysiological evidence making it a prime candidate for anti-inflammatory nutritional interventions.
  • The Standard American Diet is filled with pro-inflammatory highly refined and processed foods that are laden with excessive amounts of sugar and unhealthy fats thus promoting inflammatory pathways that exacerbate disease.
  • The genesis of the inflammation is now believed to start in part in the intestinal and pulmonary microbiomes with the loss of immune tolerance. The intestinal microbiome is highly responsive to whole food dietary alterations.
  • Uric acid, a by product of fructose metabolism, is becoming a known driver of inflammasome activation and local tissue inflammation
  • We will discuss in depth the food choices that lower the inflammatory burden, the asthma phenotype and the food immune reactions that exacerbate disease……..

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #50 – Richard Johnson, MD – Fructose and Perinatal Issues

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

This weeks guest is my favorite researcher, Dr. Richard Johnson.
He is the Tomas Berl Professor of Medicine and the Chief of the Renal Division and Hypertension at the University of Colorado since 2008. A graduate of the University of Wisconsin, Madison, with a major in Anthropology, and a graduate of the University of Minnesota Medical School, Minneapolis, he is a physician and nephrologist whose research has focused on the role of sugar, and especially fructose, in driving obesity, diabetes, high blood pressure and kidney disease. Much of this work has explored the role of fructose metabolism, especially the generation of uric acid, in driving this phenotype, and his work has included studies ranging from molecular biology, integrative physiology, and evolutionary biology. He is the author of The Sugar Fix which introduced the first low fructose diet, and also The Fat Switch which explores the role of fructose in driving the obesity epidemic. His newest book, Nature Wants Us To Be Fat, is a tour de force of the entire pathway of survival via metabolic events in the body related to fructose and the polyol pathway. This is a must read book.
This podcast will follow up on the original conversation, podcast #14, and the exceptional work of Dr. Johnson this time looking at how we are mismatched metabolically for the environment of modern America and our food systems from the maternal health and perinatal perspective.
Enjoy,
Dr. M

1 2 … 7