Tag Archives: cvd

Dr. M’s Women and Children First Podcast #54 – Doug Thompson, DDS – Teeth and Systemic Health

 

 

 

 

 

 

 

 

Today’s guest is Dr. Doug Thompson,  a 27 year veteran of dentistry since he graduated from the University of Michigan School of Dentistry in 1996. Dr. Thompson is a teacher, researcher and trail blazer in the field of modern dentistry. Today we travel down paths that lead to explanations as to why oral health is so important to systemic and truly whole human health. We look back in time and follow a timeline to the present-day research that says that we have scientific knowledge through laboratory study that the oral microbiome, the bacteria that reside with the oral cavity, as well as the oral system’s function has far reaching effects on the heart, the intestines, pregnancy and general metabolic health. Over the decades, Dr. Thompson realized that the science needed a portal to the masses and other dental professionals. Usher in the project called the Wellness Dentistry network circa 2015 which is an internet-based community of dentists with a keen awareness of how oral conditions affect whole-body health. It is a forum for Dr. Thompson and colleagues to use research to develop advanced practice ideas to thwart systemic health concerns that may arise from oral health dysfunction. On his website, Integrative Oral Medicine, Dr. Thompson states that he believes in an interdisciplinary treatment model that coordinates dental care with other medical practitioners for total body health care for his patients. He employs advanced DNA bacterial testing methods and other leading-edge dental science to enable early risk assessment and personalized treatment planning. To me this remains the future of all healthcare disciplines, collaboration, cooperation and patient centered. Let us dive into the oral cavity with Doug Thompson.
Enjoy,
Dr. M

 

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 27

Let us head back to the headwaters of HDL biology to find some more answers. If you did not read the original HDL piece or remember the basics of HDL biology, go back to Newsletter V13 #15 for a review. HDL as an associated biomarker of death risk has a U shaped curve with higher all cause mortality at very low and high levels of volume. Let us understand why? (Madsen et. al. 2017) Anything that causes more LDL, low density lipoproteins, to stay in circulation will raise one’s risk of ASCVD or heart attack. The historical reality (as I have discussed for years) for why we would have these genomic mutations to have more LDL particles in circulation is 1) as a protection mechanism against bacterial infections which were common for thousands of years. The HDL and LDL particles have receptors on their surface to grab bacterial cell wall debris like LTE or LPS and remove them via the liver. This is a massive beneftit to the human species until recent times. 2) as a storage mechanism for calories/recirculation of metabolically expensive cholesterol. (Maile et. al. 2020)(Feng et. al.. 2019)(Trinder et. al. 2021)…….
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 16

Cholesterol VII- Follow up
It is imperative that all readers know that any time you go against conventional wisdom, you run the risk of negative reactions from providers of care that disagree or do not know about this depth of hypothetical disease etiology. This set of lipid and cardiology articles was meant to stimulate the reader to think beyond the simple answer that “statin medications” and cholesterol lowering are the primary or only answers to coronary artery heart disease. The treatment of any disease must start at the headwaters of pathophysiological dysfunction. To wait until a medicine is the only way to a healthy home is not in anyones best interest…. Also, the Pollution Detectives leader Dr. Francis Koster pens an article.
Enjoy,
Dr.M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 15

High Density Lipoprotein – We are going to take a deep look at this very complex biological topic. Bear with me as in the end it will all make more sense as to why “good cholesterol” is not inherently good or bad as much as it just is. Our lifestyle decisions are in effect making a biological process good or bad. That is my scientific understanding at this time. We also look at COVID19 and the effects on the heart this week.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 14

Cholesterol Part V – What to do?
I hope that over the last four weeks I have sufficiently laid the case for heart disease as a complex disorder that is far from just a cholesterol/lipoprotein issue. It is vastly more complex than this especially with the new emerging data on the actions of high density lipoproteins, HDL, in reverse cholesterol and other molecule removal from circulation. In the next weeks newsletter, we will look at HDL. Somewhere in the near future, I will synthesize further recent work linking CVD, immunobiology and obesity.
Also, GLP Obesity drugs for teens and others….
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 12

Cholesterol Lipid Hypothesis Part III

So far, I have put forth some hypotheses that are controversial and raise questions about the American College of Cardiology guidelines. This is fine with me because this is about stimulating a conversation about disease etiology and treatment. Readers are never encouraged to go against their physician’s recommendations. The choice to change a current therapeutic regimen is solely between the patient and their provider and frankly is likely predicated on how much damage has occurred over one’s current lifetime coupled with genetic risk and the ability to alter lifestyle risk factors effectively…..and a discussion on avoiding inflammatory bowel disease.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 11

This week it is: Cholesterol Lipid Hypothesis Part II

The hypothesis: cholesterol and lipoproteins like LDL are inherently good and necessary unless they become unbalanced either through genetics and most definitely lifestyle choices. From last week: It turns out that the carrier lipoproteins like LDL and HDL cholesterol are an ancient part of our innate immune system that have an important function in fighting infection. We have always used these lipoproteins to clear infectious material before they can do damage…. Plus some research on head trauma as well as the recipe of the week.
Enjoy,
Dr. M