Tag Archives: vaccine

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 37

Coronavirus Update 69.

Quick Hits and other musings –
1) In the interview with Dr. Offit there were a few big take aways:
  • Boosters for non risk based teen and young adults are unlikely to provide benefit while offering a small but real level of risk from myocarditis
  • Boosters are offering minimal benefit to the nation from a transmission perspective. At best 8-12 weeks of protection against symptomatic disease
  • Dr. Offit voted against adding omicron antigens to this fall’s booster as there was limited data that it would any benefit. He was in the minority at the FDA advisory meeting, thus this fall’s booster will have new strain genetics in it
  • The boosters could, not shown yet in humans, block future variant immunity to newer strains through viral immune imprinting

A lot more this week to digest.

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 35

Coronavirus Update #68

At this point the fundamentals completely point to a world of Covid mitigation based on personal risk tolerance and previous vaccination and/or disease. It no longer makes any sense for the entire population to be asked to change the way they live and exist. The messaging remains a struggle for me as people including the heads of major health organizations are pushing for measures beyond what is logical. Messaging continues to be unrealistic regarding Covid for society at large. Why?

We tackle these questions and more this week.

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 33

Coronavirus Update 67

Natural infection provides a much better route to transmission protection than intramuscular systemic vaccination because of the induction of mucosal immunity via IgA and tissue resident T cells. (Tang et. al. 2022) If you can tolerate a natural infection without much morbidity, this seems to be a reasonable choice at this time. This is especially important now with the immune escaping variants of Omicron lineage and the reality of the current vaccine booster pool is lackluster in its effect on transmission. This calculus may change dramatically with a newer Omicron BA.5 specific vaccine that is in the works. And much more this week!

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 31

Coronavirus Update #66

This week is another close look at the current variants of the Omicron lineage, especially BA.5. What is the deal with this strain? Is it causing more heart ache in the United States or just an annoying highly infectious variant? In my opinion, when we have global flairs of Covid 19, there is clear evidence now that individuals that are immune compromised have unwittingly become breeding grounds for genomic mutations in SARS2 leading to variants of concern. These variants become our new circulating troublemakers. Thus, in my opinion, we should be making vaccines in this country that are high quality and targeted to the current strain. Then we should be releasing it worldwide very quickly to people in immune compromised states. This should have the effect of slowing down these emerging VOC’s that are evading our natural and vaccine induced immunity. Finally, we end with a discussion of chronic rhino sinusitis.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 29

Coronavirus Update #65

This week we take another and deeper dive into PACS or long covid. What are the risk factors for it? How does the intestinal microbiome play out in this space? Are there certain bacteria that are associated with a negative outcome? Can we alter them to our advantage? We also take a closer look at the current variants of the Omicron lineage. Finally, we end with a discussion of social media concerns.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issues 21/23, Covid Updates 61/62

Coronavirus Update #61 and 62 – This audiocast newsletter looks further into the new variants and other emerging data sets. More information on boosters, infection risks and opinions from Paul Offit and Monika Gandhi. Plus a look at Adenoviral hepatitis and formula issues.

 

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issues 13/15, Covid Updates 57/58

Coronavirus Update #57 and 58 – This audiocast newsletter is a quick hits look at the new variants and other emerging data sets.

We are in an endemic state with SARS2/Covid19. What are the new norms? Do you need a booster dose? Do we know why some people suffer neurological problems? What is affecting the blood brain barrier? These questions and a few others are explored this week.
Be well,
Dr. M

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