Tag Archives: sars2

Dr. M’s SPA Newsletter Audiocast Volume 11 Issues 33 and 35 Covid Update #41/42

A few people are asking about the need to vaccinate if you have already had COVID natural illness. What is the story here? Hot off of the press from Cell Reports Medicine, we see: “Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based immune responses. SARS-CoV-2 spike binding and neutralizing antibodies exhibit a bi-phasic decay with an extended half-life of >200 days suggesting the generation of longer-lived plasma cells. SARS-CoV-2 infection also boosts antibody titers to SARS-CoV-1 and common betacoronaviruses. In addition, spike-specific IgG+ memory B cells persist, which bodes well for a rapid antibody response upon virus re-exposure or vaccination. Virus-specific CD4+ and CD8+ T cells are polyfunctional and maintained with an estimated half-life of 200 days. Interestingly, CD4+ T cell responses equally target several SARS-CoV-2 proteins, whereas the CD8+ T cell responses preferentially target the nucleoprotein, highlighting the potential importance of including the nucleoprotein in future vaccines. Taken together, these results suggest that broad and effective immunity may persist long-term in recovered COVID-19 patients.” (Cohen et. al. 2021)

Read more for COVID #41……https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter/988-volume-11-letter-33-coronavirus-update-42

Read more for COVID #42……https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter/994-coronavirus-update-42

Happy listening

Dr. M

Dr. M’s SPA Newsletter Volume 11 Issue 31 Covid Update #40

It is time for a change of direction for me and my vaccine thoughts. A lot of risk analysis this week in children and opinions on masking to be in schools. I have been steadfastly in the push to vaccinate high risk kids over age 12 years only and all else make individual choices. The data keeps shifting and the risk of a potential concern is increasing for adolescents. Read on….
Quick hits
1) COVID mRNA vaccines for 12 and over – a few days ago, I had the pleasure of interviewing Dr. Danny Benjamin, Professor of Pediatric Infectious Diseases at Duke University and Principal Investigator on the NC school COVID study, about the COVID vaccine, variants and risk factors for problems in children. He is a brilliant and thoughtful teacher and someone that I truly trust. Our interview will be live in 1 – 2 weeks at the Women and Children First Podcast on Apple podcasts. However, there was one HUGE takeaway that I wanted to share now.
According to Dr. Benjamin, the COVID vaccine has already surpassed the necessary amount of time and number of inoculated children over 12 years of age to steadfastly discuss safety as a net known entity. In the history of vaccine development, there has never been a case of a new unknown side effect being discovered 6 months post any individual vaccination if enough people have been vaccinated to see a signal….. Read More Here: https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter/977-volume-11-letter-31-coronavirus-update-40

Dr. M’s SPA Newsletter Volume 11 Issue 27 Covid Update #38

Just when you think that the information on SARS2 Covid19 is slowing to a crawl with new discovery, a favorite researcher publishes a truly remarkable bit of scientific discovery. Dr. Alessio Fasano is featured below in Number 6 and his work is really important. A little science heavy but critical for children. There is a take home summary as well. Don’t miss this information.
Quick hits
1) CDC data on adolescent hospitalizations: COVID-19 adolescent hospitalization rates from COVID-NET peaked at 2.1 per 100,000 in early January 2021, declined to 0.6 in mid-March, and rose to 1.3 in April. Among hospitalized adolescents, nearly one third required intensive care unit admission, and 5% required invasive mechanical ventilation; no associated deaths occurred….. Read more at this link: https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter/964-volume-11-letter-27-coronavirus-update-38

Dr. M’s SPA Newsletter Volume 11 Issue 25 Covid Update #37

 

What are the latest data trends with COVID and children? What vaccine related issues have arisen? We answer these questions and more!

Quick hits

1) Sequelae following a moderate to severe COVID infection continue to plague medical systems. In a new study in the British Medical Journal, we see a 14% increased risk of developing new onset clinical conditions.

“14% of adults aged ≤65 who were infected with SARS-CoV-2 (27 074 of 193 113) had at least one new type of clinical sequelae that required medical care after the acute phase of the illness, which was 4.95% higher than in the 2020 comparator group. The risk for specific new sequelae attributable to SARS-Cov-2 infection after the acute phase, including chronic respiratory failure, cardiac arrythmia, hypercoagulability, encephalopathy, peripheral neuropathy, amnesia (memory difficulty), diabetes, liver test abnormalities, myocarditis, anxiety, and fatigue, was significantly greater than in the three comparator groups (2020, 2019, and viral lower respiratory tract illness groups).” (Daugherty et. al. 2021)……….

Read More: Link

Enjoy,

Dr. M