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Coronavirus Update #68
At this point the fundamentals completely point to a world of Covid mitigation based on personal risk tolerance and previous vaccination and/or disease. It no longer makes any sense for the entire population to be asked to change the way they live and exist. The messaging remains a struggle for me as people including the heads of major health organizations are pushing for measures beyond what is logical. Messaging continues to be unrealistic regarding Covid for society at large. Why?
We tackle these questions and more this week.
Dr. M


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Issue 34


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Coronavirus Update 67
Natural infection provides a much better route to transmission protection than intramuscular systemic vaccination because of the induction of mucosal immunity via IgA and tissue resident T cells. (Tang et. al. 2022) If you can tolerate a natural infection without much morbidity, this seems to be a reasonable choice at this time. This is especially important now with the immune escaping variants of Omicron lineage and the reality of the current vaccine booster pool is lackluster in its effect on transmission. This calculus may change dramatically with a newer Omicron BA.5 specific vaccine that is in the works. And much more this week!
Dr. M


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Dr. Paul A. Offit is Director of the Vaccine Education Center and professor of pediatrics in the Division of Infectious Diseases at Children’s Hospital of Philadelphia. He is the Maurice R. Hilleman Professor of Vaccinology at the Perelman School of Medicine at the University of Pennsylvania.
Dr. Offit is an internationally recognized expert in the fields of virology and immunology, and was a member of the Advisory Committee on Immunization Practices to the Centers for Disease Control and Prevention. He is a member of the Food and Drug Administration Vaccines and Related Biological Products Advisory Committee, a member of the Institute of Medicine and co-editor of the foremost vaccine text, Vaccines.
He is a scientist, a skeptic, a thinker and an individual deeply passionate about children’s health.
This week we sit down to discuss Covid, vaccines and children’s health.
I hope that you enjoy my conversation with Dr. Offit,
Dr. M


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