metabolic disease

Dr. M’s Women and Children First Podcast #38 Donald Layman, PhD – Protein

Donald Layman is currently a Professor Emeritus at the University of Illinois Urbana-Champaign College of Agricultural, Consumer and Environmental Sciences in the department of Food Science & Human Nutrition. Dr. Laymen earned his Bachelors Degree in Science in Chemistry and Masters Degree in Science in Biochemistry at Illinois State University. He then completed his Doctorate Ph.D. in Human Nutrition Nutrition and Biochemistry at the University of Minnesota.
His laboratory is working to define protein and amino acid requirements and the interrelationship between dietary protein and carbohydrates in adult health. The research is focused on the impact of diet and exercise on adult health problems of obesity, type 2 diabetes and the Metabolic Syndrome. Exercise is of obvious importance to health in maintenance of lean body mass, energy expenditure and weight control. Surprisingly little is known about amino acid requirements during exercise or the impact of amino acids on metabolic regulation. His group has helped to define roles of the branched chain amino acids (BCAA) in skeletal muscle metabolism. BCAA provide an important energy source for muscle during exercise and also serve as a critical regulator of muscle protein synthesis during recovery. During exercise, oxidation of BCAA increases, resulting in production of the amino acid alanine and a rapid decline in plasma levels of BCAA. Amino acid supplements prevent this decline in plasma amino acids, enhance recovery of muscle protein synthesis and interact with insulin to help stabilize blood glucose. They are continuing this research to define mechanisms for control of muscle protein synthesis and differences in dietary protein needs for men versus women and for adults with sedentary versus active lifestyles.
A very important conversation for all to understand. All ages are impacted by this knowledge.
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 52

12 years gone by! 624 newsletters down. So much has changed in the past 12 years since I began this journey of writing and learning. We wrap up the 12 year of the podcast with top ten things learned. Also touch on the mineral zinc as well as Long Distance Love Bombs.
Best to all,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 51

Coronavirus Update 76 plus other stuff
The work around Covid research is fading for me. This is now mostly a highly contagious upper respiratory infection for most. The morbidity has faded to a level where we are seeing very limited disease in children and the hospital data remains completely plateaued. Unless there is a dramatic shift in this virus, we are moving toward a world where Covid will be like the other 4 circulating coronaviruses for most of the United States population save for the high risk individuals as described throughout the pandemic.
Focus remains on self care to boost all immune activity to thwart all infections from all microbes.
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 48

This week we take a look at: Drug Induced Micronutrient Loss, Soleus Push Ups and Miror Neurons

To function at the highest and most optimal state requires providing our human engine with nutrients, both macro and micro types. By macro, I mean fats, carbohydrates and proteins. By micro, I mean minerals and vitamins which are cofactors for enzymatic activity driving the machine to normalcy of action whatever that action is. What dictates sufficiency? How do drugs disrupt this optimization success?
and much more…
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #34 Stephan Guyenet, PhD – Childhood Obesity Part IV – Neuroscience of Food Choice

This week, I sit down with Dr. Stephan J. Guyenet, a neuroscientist, thinker and educator.  After earning a BS in biochemistry at the University of Virginia, he completed a PhD in neuroscience at the University of Washington, then went on to study the neuroscience of obesity and eating behavior as a postdoctoral fellow.  He has over 12 years of history in the neuroscience research world studying neurodegenerative disease and the neuroscience of body fatness.  His mission is to advance science and public health as a researcher, science consultant, and science communicator.  Publishing a book, The Hungry Brain, in 2017, he laid out the framework for understanding how our brains work with food. It was named one of the best books of the year by Publishers Weekly and called “essential” by the New York Times Book Review.

Finally, he is the founder and director of Red Pen Reviews, which publishes the most informative, consistent, and unbiased popular health and nutrition book reviews available.

This hour long conversation is very stimulating as we dive headlong into the upstream targets of food choice and body outcome.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 32

This is Bone Health week.
As soon as you are conceived, the process of growing new bone begins in the map of DNA. The first bone cells are noted at the sixth week post conception. This process continues for many years peaking as a teenager and beginning to decline in the third decade of life. The peak decline starts in the sixth decade when sex steroids start to decline significantly. The natural process of bone development is very complicated with many hormones like vitamin D and parathyroid as well as micronutrients necessary for optimal function…..
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issues 10 and 12

SPA Audiocast Newsletter Volume 12 Letters 10 and 12

In issue 10, we look at effort and resilience. We take a look at non nutritive sweeteners and the microbiome. And finally, sugar and the risk of Inflammatory Bowel Diseases.

In issue 12, we discuss trauma and the epigenetic realities that follow these events. We look at some new research related to type 1 Diabetes following Covid infection as well as the effects that Maternal Gestational Diabetes on newborn offspring.

Enjoy,

Dr. M