nutrition

Dr. M’s SPA Newsletter Volume 14 Issue 47

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Sulfurophane and health – It is clear now that SFN stands out as a powerhouse phytochemical with profound effects on human health through the pathway of nurclear factor erythroid related 2 (NRF2). It is found abundantly in cruciferous vegetables such as broccoli, broccolini, kale, and brussels sprouts. SFN is a bioactive compound with impressive clinical potential for preventing chronic disease and optimizing cellular health, especially in oxidant impaired/overloaded states. At its core, SFN is a sulfur-rich molecule derived from glucoraphanin, a glucosinolate precursor. The transformation occurs when the enzyme myrosinase, released during the chopping or chewing of cruciferous vegetables, catalyzes the reaction. Interestingly, this enzymatic activation can also be achieved via gut microbiota when raw vegetables are absent from the diet, emphasizing the remarkable adaptability of our biology to source essential nutrients as needed for survival. (Ali et. al. 2023)

Nrf2 is a master regulator of cellular defense, orchestrating the production of detoxification enzymes, antioxidants, and other cytoprotective proteins. By activating Nrf2, sulforaphane enhances the body’s resilience to oxidative stress, a key contributor to aging, inflammation, and the development of chronic diseases such as cardiovascular disease and diabetes. Studies reveal that sulforaphane also induces Phase II detoxification enzymes, such as glutathione S-transferase, which play a vital role in neutralizing and excreting harmful toxins.

Dr. M’s SPA Newsletter Volume 14 Issue 46

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Lymphatics – Refresher

Lymphatics – a plumbing system that follows the circulatory system throughout the body including the brain where it is called the glymphatics. The function of these passively moving tubes is to transport fats around the body, clear cellular debris returning it to the liver and spleen, move fluid in and out of tissue to maintain fluid balance, transport and help immune cells function. By transporting fats , lymph is involved in vitamin movement to tissues and cells for Vitamins A, D, E, K. These are critical functions of metabolism, immunity and detoxification that when disrupted lead to chronic diseases of aging including edema, hypertension, autoimmunity and cardiovascular disease.

“Traditionally considered a passive route for transport of fluid, immune cells, and lipoproteins, lymphatics are now known to be active players in major physiological and pathophysiological processes. Until recently, lymphatic vessel dysfunction was mainly associated with primary and secondary lymphedema. Unexpectedly, however, lymphatic vascular defects have been uncovered in conditions such as obesity, cardiovas- cular disease, inflammation, hypertension, atherosclerosis, Crohn’s disease, glaucoma and various neurological disorders such as Alzheimer’s disease.” (Oliver et. al. 2021)…and a discussion on chemicals in school food.

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #82 – Megan Lyons, DCN, MBA

Megan Lyons, is a distinguished expert in personalized nutrition and wellness, with over a decade of experience in the field. As the founder of The Lyons’ Share Wellness, she has dedicated more than 14,000 hours to one-on-one nutrition consulting, assisting clients with diverse goals such as weight loss, overcoming emotional eating, managing thyroid dysfunction, and reversing prediabetes and cholesterol issues.

Her academic credentials are extensive:

  • Doctorate of Clinical Nutrition from the University of Western States
  • Master of Science in Holistic Nutrition from Hawthorn University
  • Master of Business Administration from the Kellogg School of Management at Northwestern University
  • Undergraduate degree from Harvard University

Megan is double board-certified as a Clinical and Holistic Nutritionist, and she is a graduate of the Institute for Integrative Nutrition.

In 2016, she authored the Amazon Top 10 bestseller, Start Here: 7 Easy, Diet-Free Steps to Achieve Your Ultimate Health and Happiness. Additionally, she hosts the popular podcast Wellness Your Way, where she shares actionable and motivational health information with thousands of listeners each week.

Our goal today is to highlight the realities of women’s health, hormones and breastfeeding.

Enjoy,

Dr. M

The Lyons Share

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 40/41

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Literature Review Week

Why do some people react to mosquitoes so vigorously? There is fascinating data for me in the Nature article, as I see lots of kids that react strongly to mosquitoes while others do not at all. A hyper primed immune reaction makes a lot of sense as the immune system is extra sensitive to the insult in individuals that have chronic allergic phenotypes. They are in effect polarized to see the outside world through an irritant lens and thus react in a more robust way. The cell called GD3 releases Interleukin 3 or IL-3 which is a cytokine signaling molecule that tells skin based sensory neurons to become more sensitive to allergens like house dust mites, environmental molds, and in this case mosquito saliva. Thus, the mosquito saliva induces more of the itch scratch cycle. The effect is to increase the gain sensitivity on the skin to 10. This is likely a main reason why having an allergic child take immunotherapy against allergens that they react to lowers the rheostat for all irritants. It is like a global check on the sensory system. This is another reason to consider SLIT and or SCIT immunotherapy in allergic children… Plus a discussion on the Joe Rogan podcast with Callie and Casey Means.

Enjoy,

Dr. M

 

Dr. M’s Women and Children First Podcast #80 – Deborah Tate, PhD – Studying the Obesity Epidemic

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

 

Obesity and Change – The Tech Intersection

Welcome to the podcast! Today, I am thrilled to host Dr. Deborah Tate, a distinguished professor in the Department of Nutrition at the University of North Carolina in Chapel Hill, with joint appointments in Health Behavior and Nutrition. She also holds a faculty appointment at the Nutrition Research Institute in Kannapolis, North Carolina where she explores innovative approaches to improve lifestyle behaviors that impact obesity, diabetes, and chronic disease risk. Dr. Tate is a behavioral scientist, receiving her Ph.D. in Clinical Psychology at Virginia Tech. Her research focuses on two main areas: (a) strategies for improving both short and long-term body weight regulation to reduce disease risks and (b) the development and translation of programs as alternatives to clinic-based care using digital and wearable technologies. She is known internationally for her work has published many papers in major nutrition and medical journals. Her work spans the intersection of behavioral health and obesity whereby she is a pioneer in digital health interventions. Her work has been pivotal in developing digital tools and online programs that support sustainable health changes, making access to wellness resources more inclusive and effective.

Dr. Tate has been at the forefront of harnessing technology to create lasting change, blending behavioral science with digital advancements to empower individuals and families to make improved choices. Her contributions have transformed how we think about health interventions in today’s digital age, offering scalable solutions that reach beyond traditional boundaries. Get ready for an insightful conversation with Dr. Tate as we dive into the science and the potential of digital health to foster resilience and well-being.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 39

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Section I

Understanding the Action and Use of GLP-1 Agonists in Children – A Pediatrician’s Viewpoint

The United States, like much of the developed world, is facing increasing rates of childhood obesity and related health concerns. Despite years of research and various efforts, addressing this public health issue remains a complex challenge.

This article reviews the potential mechanisms, benefits, and considerations for using GLP-1 agonists in children based on the current scientific understanding. While early research is promising, the application of these treatments in children requires careful consideration and should always be done in consultation with a healthcare provider.

As a pediatrician, I recognize that while the science behind these treatments is evolving, it’s important to remember that individual responses to treatments can vary. For children, every approach needs to be carefully weighed, considering their unique developmental needs…..

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #79 – Robert Lustig, MD – Obesity Epidemic

Podcast: Play in new window | Download

Subscribe: Email | RSS | More

Welcome to the podcast! Today, I am thrilled to have a true pioneer in the field of metabolic health, Dr. Robert Lustig, MD, joining us. Dr. Lustig is a neuroendocrinologist and Professor Emeritus of Pediatrics in the Division of Endocrinology at the University of California, San Francisco. He is best known for his groundbreaking work on the intersection of diet, obesity, and metabolic disease, particularly his deep dive into the role of sugar as a driving force behind many of today’s chronic health issues.

As the author of several influential books, including Fat Chance, The Hacking of the American Mind and Metabolical, Dr. Lustig has been a vocal advocate for public health, helping to raise awareness about the harmful effects of processed foods, particularly refined sugars. His research has been instrumental in shifting the conversation around nutrition, focusing on the biological impacts of sugar and the ways it contributes to insulin resistance, obesity, and metabolic syndrome. His most recent paper entitled Obesogens, A Unifying Theory for the Global Rise in Obesity in the International Journal of Obesity – Nature is a ground stirring take on the current research.

We are excited to explore his latest insights into metabolic health and the science of obesity, and how we can apply this knowledge to improve our own well-being. Let’s welcome Dr. Lustig to the show!

Dr. M

1 2 … 13