SPA Audiocast Newsletter Volume 12 Letters 10 and 12
In issue 10, we look at effort and resilience. We take a look at non nutritive sweeteners and the microbiome. And finally, sugar and the risk of Inflammatory Bowel Diseases.
In issue 12, we discuss trauma and the epigenetic realities that follow these events. We look at some new research related to type 1 Diabetes following Covid infection as well as the effects that Maternal Gestational Diabetes on newborn offspring.
Dr. Victoria Maizes is executive director of the University of Arizona Center for Integrative Medicine, chief of the UA Division of Integrative Medicine and a professor of medicine, family medicine and public health. Internationally recognized as a leader in integrative medicine, she stewarded the growth of the Arizona Center for Integrative Medicine from a small program educating four residential fellows per year to a designated “Center of Excellence” that trains more than 500 residents and fellows annually.
Dr. Maizes has pioneered multiple innovative educational programs including the Integrative Family Medicine Program, and Integrative Medicine in Residency, two national models for educating primary care physicians. As founding co-chair of the education committee of the Consortium of Academic Health Centers for Integrative Medicine—the mission of which is to promote integrative medicine, she has led a team of educators in developing objectives for medical students in integrative medicine.
Her passion for women’s health makes her ideal for a discussion on fertility and the best path forward for a woman wanting to become a mother. Her book, Be Fruitful, is a road map leading to the best pregnancy and child outcomes. We discuss the root causes of infertility and maternal disease. Dr. Maizes teaches us the pathway to be followed for a mother to be in order to unwind the antecedent risk factors for infertility and disease.
I hope that you enjoy my conversation with Dr. Maizes,
Dr. Randy Jirtle joins the show today to discuss his groundbreaking research that ushered in the era of epigenetics. Time Magazine nominated him for person of the year in 2007 and had this to say about him: “Dr. Jirtle’s pioneering work in epigenetics and genomic imprinting has uncovered a vast territory in which a gene represents less of an inexorable sentence and more of an access point for the environment to modify the genome. His trailblazing discoveries have produced a far more complete and useful understanding of human development and diseases” — Time Magazine. This interview is ground zero for the Women and Children First Podcast as we discuss the underpinnings or mechanisms of disease risk for all humans as it relates to the environmental inputs of our lives that are driving health or disease at both the pregnancy and post natal periods. We look specifically at how maternal nutrition and later chemical exposure directly affected the health of the agouti mouse offspring. This experiment was the first of its kind and paved the way for a complete shift in human disease understanding. For parents, this podcast is really the beginning of everything that I am trying to convey regarding a healthy pregnancy and childhood. Without this interview, the following interviews will be more difficult to understand. The picture becomes very clear once his research is cemented in our minds.
His biography is as follows: Professor of Epigenetics at the Department of Biological Sciences, North Carolina State University, Raleigh, NC, and a Senior Scientist at McArdle Laboratory for Cancer Research at the University of Wisconsin, Madison, WI. He was previously professor of radiation oncology and associate professor of pathology at Duke University, Durham, NC, where he had been a faculty member since 1977. He graduated with a B.S. degree in nuclear engineering in 1970 and a Ph.D. degree in radiation biology in 1976, from the University of Wisconsin-Madison. His awards list is long but the key to Dr. Jirtle is that he is a curious thinker and we are grateful for this.
Please enjoy my conversation with Dr. Randy Jirtle,