cardiovascular disease

Dr. M’s Women and Children First Podcast #65 – Mark Houston, M.D. – Cardiovascular Health

Dr. Mark Houston is a thinker and researcher into the root causes of cardiovascular disease and metabolism. He graduated from Rhodes College in Memphis, Tennessee summa cum laude in Chemistry before graduating with honors from Vanderbilt Medical School. He completed his medical internship and residency at the University of California, San Francisco, then returned to Vanderbilt Medical Center where he was chief resident in medicine and served on the full- time faculty until 2012. He is the current director of the hypertension Institute where he and his team develop novel approaches to hypertension and ASCVD by attending to root biological causes of disease. He also has a Master’s degree in Human Nutrition from the University of Bridgeport, Connecticut, and a Masters of Science degree in Functional and Metabolic Medicine from the University of South Florida in Tampa Florida. He has written hundreds of papers, books and chapters on cardiovascular disease. He is one of the top researchers in the preventative cardiology space and he is here today to share his wisdom.
His book credits:
Handbook of Antihypertensive Therapy
Vascular Biology for the Clinician
What Your Doctor May Not Tell You About Hypertension
Hypertension Handbook for Students and Clinicians
The Hypertension Handbook
What Your Doctor May Not Tell You About Heart Disease.
Please enjoy my conversation with Dr. Mark Houston,
Dr. M
Hypertension Institute

Dr. M’s Women and Children First Podcast #54 – Doug Thompson, DDS – Teeth and Systemic Health









Today’s guest is Dr. Doug Thompson,  a 27 year veteran of dentistry since he graduated from the University of Michigan School of Dentistry in 1996. Dr. Thompson is a teacher, researcher and trail blazer in the field of modern dentistry. Today we travel down paths that lead to explanations as to why oral health is so important to systemic and truly whole human health. We look back in time and follow a timeline to the present-day research that says that we have scientific knowledge through laboratory study that the oral microbiome, the bacteria that reside with the oral cavity, as well as the oral system’s function has far reaching effects on the heart, the intestines, pregnancy and general metabolic health. Over the decades, Dr. Thompson realized that the science needed a portal to the masses and other dental professionals. Usher in the project called the Wellness Dentistry network circa 2015 which is an internet-based community of dentists with a keen awareness of how oral conditions affect whole-body health. It is a forum for Dr. Thompson and colleagues to use research to develop advanced practice ideas to thwart systemic health concerns that may arise from oral health dysfunction. On his website, Integrative Oral Medicine, Dr. Thompson states that he believes in an interdisciplinary treatment model that coordinates dental care with other medical practitioners for total body health care for his patients. He employs advanced DNA bacterial testing methods and other leading-edge dental science to enable early risk assessment and personalized treatment planning. To me this remains the future of all healthcare disciplines, collaboration, cooperation and patient centered. Let us dive into the oral cavity with Doug Thompson.
Dr. M


Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 27

Let us head back to the headwaters of HDL biology to find some more answers. If you did not read the original HDL piece or remember the basics of HDL biology, go back to Newsletter V13 #15 for a review. HDL as an associated biomarker of death risk has a U shaped curve with higher all cause mortality at very low and high levels of volume. Let us understand why? (Madsen et. al. 2017) Anything that causes more LDL, low density lipoproteins, to stay in circulation will raise one’s risk of ASCVD or heart attack. The historical reality (as I have discussed for years) for why we would have these genomic mutations to have more LDL particles in circulation is 1) as a protection mechanism against bacterial infections which were common for thousands of years. The HDL and LDL particles have receptors on their surface to grab bacterial cell wall debris like LTE or LPS and remove them via the liver. This is a massive beneftit to the human species until recent times. 2) as a storage mechanism for calories/recirculation of metabolically expensive cholesterol. (Maile et. al. 2020)(Feng et. al.. 2019)(Trinder et. al. 2021)…….
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 16

Cholesterol VII- Follow up
It is imperative that all readers know that any time you go against conventional wisdom, you run the risk of negative reactions from providers of care that disagree or do not know about this depth of hypothetical disease etiology. This set of lipid and cardiology articles was meant to stimulate the reader to think beyond the simple answer that “statin medications” and cholesterol lowering are the primary or only answers to coronary artery heart disease. The treatment of any disease must start at the headwaters of pathophysiological dysfunction. To wait until a medicine is the only way to a healthy home is not in anyones best interest…. Also, the Pollution Detectives leader Dr. Francis Koster pens an article.

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 15

High Density Lipoprotein – We are going to take a deep look at this very complex biological topic. Bear with me as in the end it will all make more sense as to why “good cholesterol” is not inherently good or bad as much as it just is. Our lifestyle decisions are in effect making a biological process good or bad. That is my scientific understanding at this time. We also look at COVID19 and the effects on the heart this week.


Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 14

Cholesterol Part V – What to do?
I hope that over the last four weeks I have sufficiently laid the case for heart disease as a complex disorder that is far from just a cholesterol/lipoprotein issue. It is vastly more complex than this especially with the new emerging data on the actions of high density lipoproteins, HDL, in reverse cholesterol and other molecule removal from circulation. In the next weeks newsletter, we will look at HDL. Somewhere in the near future, I will synthesize further recent work linking CVD, immunobiology and obesity.
Also, GLP Obesity drugs for teens and others….
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 13

Cholesterol Lipid Hypothesis Part IV – Endothelial Dysfunction
How does an artery clog? Let us recap a little at this time. 1) Cholesterol and lipoproteins are significant and necessary for pathology to develop but not the only player in heart disease and atherosclerosis. I believe that inflammation is the root cause of the problem driving the lipid imbalance and plaque formation. 2) Lipoproteins are produced and recycled every day in order to deliver energy to tissues around the body via triglycerides and are a part of the ancient innate immune system. They are primed and ready to fight all systemic pathogens that are trying to hurt us. 3) Your genetic makeup may dictate whether you produce and/or recycle more cholesterol/lipoproteins than are advantageous in our current environment….Plus a discussion on acne.
Dr. M