Tag Archives: microbiome

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 37

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Coronavirus Update 69.

Quick Hits and other musings –
1) In the interview with Dr. Offit there were a few big take aways:
  • Boosters for non risk based teen and young adults are unlikely to provide benefit while offering a small but real level of risk from myocarditis
  • Boosters are offering minimal benefit to the nation from a transmission perspective. At best 8-12 weeks of protection against symptomatic disease
  • Dr. Offit voted against adding omicron antigens to this fall’s booster as there was limited data that it would any benefit. He was in the minority at the FDA advisory meeting, thus this fall’s booster will have new strain genetics in it
  • The boosters could, not shown yet in humans, block future variant immunity to newer strains through viral immune imprinting

A lot more this week to digest.

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 36

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Biome Depletion Theory or Biota Alteration Theory
When we look at risk of disease over time in humans, we need to take stock in what was supposed to be versus what is. If we become mismatched genetically to the environment that we find ourselves in, then we will begin to suffer disease. The work of Dr. William Parker and colleagues is very fascinating here. His understanding of our immune solvency takes us back to a time when macrobes like parasites lived with us in a semi-symbiotic way. Most of them were harmless where a few were pathogenic. This matters tremendously because as we are learning, the microbes that exist within us play a major role in tuning the immune system towards tolerance and effective pathogen killing.
A lot to explore here,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 35

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Coronavirus Update #68

At this point the fundamentals completely point to a world of Covid mitigation based on personal risk tolerance and previous vaccination and/or disease. It no longer makes any sense for the entire population to be asked to change the way they live and exist. The messaging remains a struggle for me as people including the heads of major health organizations are pushing for measures beyond what is logical. Messaging continues to be unrealistic regarding Covid for society at large. Why?

We tackle these questions and more this week.

Dr. M

Dr. M’s Women and Children First Podcast #27 – Dr. Paul Offit – Covid Vaccines

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Dr. Paul A. Offit is Director of the Vaccine Education Center and professor of pediatrics in the Division of Infectious Diseases at Children’s Hospital of Philadelphia. He is the Maurice R. Hilleman Professor of Vaccinology at the Perelman School of Medicine at the University of Pennsylvania.

Dr. Offit is an internationally recognized expert in the fields of virology and immunology, and was a member of the Advisory Committee on Immunization Practices to the Centers for Disease Control and Prevention. He is a member of the Food and Drug Administration Vaccines and Related Biological Products Advisory Committee, a member of the Institute of Medicine and co-editor of the foremost vaccine text, Vaccines.

He is a scientist, a skeptic, a thinker and an individual deeply passionate about children’s health.

This week we sit down to discuss Covid, vaccines and children’s health.

I hope that you enjoy my conversation with Dr. Offit,

 

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 29

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Coronavirus Update #65

This week we take another and deeper dive into PACS or long covid. What are the risk factors for it? How does the intestinal microbiome play out in this space? Are there certain bacteria that are associated with a negative outcome? Can we alter them to our advantage? We also take a closer look at the current variants of the Omicron lineage. Finally, we end with a discussion of social media concerns.

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #24 – Dr. Lindsey Albenberg – Nutrition, microbiome and the bowel.

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My guest this week is Dr. Lindsey Albenberg. We sit down to discuss all things gastrointestinal as it relates to children, nutrition, inflammation and health. Dr. Albenberg is a physician in the Division of Gastroenterology, Hepatology and Nutrition and a member of the research team in the Center for Pediatric Inflammatory Bowel Disease at Children’s Hospital of Philadelphia. She primarily studies inflammatory bowel diseases (IBD) as they relate to nutrition, the microbiome and overall health. She has been published in top journals including Gut, Journal of Clinical Investigation and Inflammatory Bowel Diseases. She is known for her teaching skills and has won many awards as a resident and an attending physician.

We discuss many layers of the evolving understanding of where the touch points are in the development of a dysfunctional microbiome and subsequently inflammatory diseases. She gives us high quality dietary information based on the current data for how to approach food with children and adults. We delve into Covid 19 a little and some other tidbits of useful take home points.

I hope that you will enjoy my conversation with Dr. Lindsey Albenberg,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 25

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Coronavirus Update 63 plus other stuff – Lots on boosters today while the persistent world of Covid exposure drags on. Omicron US strains: newer variant BA.2 makes up 35% of current case volume based on different parts of the country while omicron BA BA 1.1.529 is at 6% and B 2.12.1 is 59%. Delta is gone by competition. Cases are increasing in some cities with little increase in hospital morbidity and mortality. In essence we are still fairing quite well in the new norm. Quick Hits and other musings!
Dr. M

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