Newsletter

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 50

The fundamentals are these: Age related changes that lead to neuronal loss and cognitive decline are related to loss or reduction of myokine release, systemic inflammation, insulin resistance, reactive oxygen induced mitochondrial stress, DNA mutations and poor protein intake.
First, exercise releases chemicals called myokines which are cell signaling molecules that have the job of telling other cells what to do via changes in gene expression, protein transcription and much more. The prototypical change is the increase of a substance called brain derived neurotrophic factor, BDNF, for short. BDNF is critical for brain cell mitochondrial biogenesis. BDNF promotes many developmental functions in the brain, including neuronal cell survival, differentiation, migration, dendritic arborization, and synaptic plasticity. Regular exercise promotes a progressive increase in BDNF protein for up to at least 3 mo………
Enjoy,
Dr.M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 49

Covid Update #75

All new omicron based variants are extremely infectious but not really dangerous anymore to immunocompetent people. They are evading prior immunity as well as all vaccines to varying degrees. Morbidity remains very low now. The current bivalent vaccines are not showing any improvement over the ancestral vaccine. Death remains almost zero for all healthy previous infected or vaccinated individuals. This is likely the new norm from here on out.

This week we cover covid, vaccine effectiveness, skeletal muscle and dementia, human protein needs and function.

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 48

This week we take a look at: Drug Induced Micronutrient Loss, Soleus Push Ups and Miror Neurons

To function at the highest and most optimal state requires providing our human engine with nutrients, both macro and micro types. By macro, I mean fats, carbohydrates and proteins. By micro, I mean minerals and vitamins which are cofactors for enzymatic activity driving the machine to normalcy of action whatever that action is. What dictates sufficiency? How do drugs disrupt this optimization success?
and much more…
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 47

Covid Newsletter #74. Why are we seeing massive waves of RSV and Influenza A right now? These viruses normally circulate in the winter only. The answer is nuanced, but likely primarily because of the pandemics social distancing and hygiene activity. During the 2020-2022 cycle of Covid fear and mitigation of viral risk, most of us avoided the normal trappings of viral spread. We masked avoiding the viral droplet portal of entry most commonly used. We kept our children semi isolated from other children where most year to year viral transmission events occur. We practiced enhanced hand washing and sanitizing reducing natural viral spread through contact. In essence we stopped the normal propagation of respiratory virus for 2 years. A whole cycle of children between 0 and 2 years old are RSV and flu immune naive leading to a perfect host pool for spread. The 2 to 18 year olds have had a long pause in exposure reducing circulating virus specific antibodies to negligible levels leading to stronger infections and more spread. Anyone who has a child in college (me) has seen infection after infection pound these students this fall. It seems like they are always dealing with a viral illness. Immunity country wide will return in the coming year to these viral illnesses reverting to the old reality of winter predominance.
Quick Covid Hits and other musings –
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 46

This week we look at PFAS Chemicals – Otherwise called “Forever Chemicals”

Per- and polyfluoroalkyl substances (PFAS) or forever chemicals are being found all throughout the world as their use has risen over the past 6 plus decades. PFAS are a family of chemicals known as POPS or persistent organic pollutants as they are reported to not break down easily. They have been found in products like Teflon based nonstick cookware, Scotch Guard and Gortex stain-resistant carpeting and clothing, dental floss, commercial firefighting foams and many types of food packaging. Unfortunately, these toxins have been detected in drinking water, house dust and foods/beverages of common consumption…..
We will also discuss children’s strengths and hospitals.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 45

Covid Update # 73:
Omicron US strains: as of October 22nd data – variants make up: BA.4.6 is 11%, BA.2.75 is 2%, BF.7 is 7%, BA.5 is 62%, BQ.1 is 9%, BQ1.1 is 7%
BA.5 is losing ground to many new Omicron variant offshoots. BF.7, BQ.1 and BQ1.1 are very interesting as they are apparently more infectious than BA.5. That is amazing.
We look at new PASC Long Covid data as well as the world of vaccine effectiveness. And much more…
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 44

Medication errors are a major risk for morbidity and mortality nationally. The number affected skyrockets into the hundreds of thousands when we look at the countless side effects that do not cause death but leave us miserable and harmed.
When it comes to the children that we treat, physicians and care providers should refuse to give a medicine unless it is absolutely necessary. We explore these topics, a literature review and omega three fatty acids this week.
Enjoy,
Dr. M

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