Newsletter

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 1

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Covid update #77 with quick hits on vaccines in young adults, POTS or hypotension following Covid 19 as well as obesity and Sars2. Non covid research looking at the brain.

From Nature Communications: “Parkinson’s disease (PD) may start in the gut and spread to the brain. To investigate the role of gut microbiome, we conducted a large-scale study, at high taxonomic resolution, using uniform standardized methods from start to end… Here we show that over 30% of species, genes and pathways tested have altered abundances in PD, depicting a widespread dysbiosis.”

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 52

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12 years gone by! 624 newsletters down. So much has changed in the past 12 years since I began this journey of writing and learning. We wrap up the 12 year of the podcast with top ten things learned. Also touch on the mineral zinc as well as Long Distance Love Bombs.
Best to all,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 51

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Coronavirus Update 76 plus other stuff
The work around Covid research is fading for me. This is now mostly a highly contagious upper respiratory infection for most. The morbidity has faded to a level where we are seeing very limited disease in children and the hospital data remains completely plateaued. Unless there is a dramatic shift in this virus, we are moving toward a world where Covid will be like the other 4 circulating coronaviruses for most of the United States population save for the high risk individuals as described throughout the pandemic.
Focus remains on self care to boost all immune activity to thwart all infections from all microbes.
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 50

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The fundamentals are these: Age related changes that lead to neuronal loss and cognitive decline are related to loss or reduction of myokine release, systemic inflammation, insulin resistance, reactive oxygen induced mitochondrial stress, DNA mutations and poor protein intake.
First, exercise releases chemicals called myokines which are cell signaling molecules that have the job of telling other cells what to do via changes in gene expression, protein transcription and much more. The prototypical change is the increase of a substance called brain derived neurotrophic factor, BDNF, for short. BDNF is critical for brain cell mitochondrial biogenesis. BDNF promotes many developmental functions in the brain, including neuronal cell survival, differentiation, migration, dendritic arborization, and synaptic plasticity. Regular exercise promotes a progressive increase in BDNF protein for up to at least 3 mo………
Enjoy,
Dr.M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 49

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Covid Update #75

All new omicron based variants are extremely infectious but not really dangerous anymore to immunocompetent people. They are evading prior immunity as well as all vaccines to varying degrees. Morbidity remains very low now. The current bivalent vaccines are not showing any improvement over the ancestral vaccine. Death remains almost zero for all healthy previous infected or vaccinated individuals. This is likely the new norm from here on out.

This week we cover covid, vaccine effectiveness, skeletal muscle and dementia, human protein needs and function.

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 48

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This week we take a look at: Drug Induced Micronutrient Loss, Soleus Push Ups and Miror Neurons

To function at the highest and most optimal state requires providing our human engine with nutrients, both macro and micro types. By macro, I mean fats, carbohydrates and proteins. By micro, I mean minerals and vitamins which are cofactors for enzymatic activity driving the machine to normalcy of action whatever that action is. What dictates sufficiency? How do drugs disrupt this optimization success?
and much more…
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 47

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Covid Newsletter #74. Why are we seeing massive waves of RSV and Influenza A right now? These viruses normally circulate in the winter only. The answer is nuanced, but likely primarily because of the pandemics social distancing and hygiene activity. During the 2020-2022 cycle of Covid fear and mitigation of viral risk, most of us avoided the normal trappings of viral spread. We masked avoiding the viral droplet portal of entry most commonly used. We kept our children semi isolated from other children where most year to year viral transmission events occur. We practiced enhanced hand washing and sanitizing reducing natural viral spread through contact. In essence we stopped the normal propagation of respiratory virus for 2 years. A whole cycle of children between 0 and 2 years old are RSV and flu immune naive leading to a perfect host pool for spread. The 2 to 18 year olds have had a long pause in exposure reducing circulating virus specific antibodies to negligible levels leading to stronger infections and more spread. Anyone who has a child in college (me) has seen infection after infection pound these students this fall. It seems like they are always dealing with a viral illness. Immunity country wide will return in the coming year to these viral illnesses reverting to the old reality of winter predominance.
Quick Covid Hits and other musings –
Enjoy,
Dr. M

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