Tag Archives: nutrition

Dr. M’s SPA Audiocast Newsletter Volume 14 Issue 28

Klotho Part II

Last week we discussed Klotho as a protein that has pleotrophic effects in the body as it relates to cellular aging. This week let us focus specifically on the brain. What are the effects of klotho as it relates to cognition and function over time? Klotho has neuroprotective effects based on studies that show that better cognitive performance in translational models over time occur with the injections of klotho. Klotho is also shown to have neuroprotective effects if naturally elevated, i.e. individuals with host genetics that promote more klotho production over time without being taken or given.

The pivitol research occurred in 2015 in a mouse model of Alzheimers Disease (AD) where Dr. Dena Dubal and colleagues looked at two groups of intervention mice with and without higher levels of Klotho. and a literature review on micro plastics and screentime.

Enjoy,

Dr. M

Dr. M’s SPA Audiocast Newsletter Volume 14 Issue 27

Klotho Part I
Ok, it is time for a potential log step shift in the human understanding of neurological decline with age starting from birth.
Enter the peptide, (C)Klotho, named after the greek goddess of fate who spins the thread of life for all. The Klotho protein was discovered by researchers looking at mice that aged faster than the general mouse population. These mice were noted to have a shortened lifespan, stunted growth, renal disease, blood vessel calcification, cardiac hypertrophy, hypertension, pulmonary disease, cognitive impairment, multi-organ atrophy and fibrosis. (Prud’homme et. al. 2022) When they looked closer, these mice were found to have hypoactive klotho proteins leading to an explosion of research over the past two decades to understand why. The next question was, could the hyperactive state provide an anti aging effect?
The answer was a resounding yes!
and a discussion on fast food.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 22

What are the main preventable etiologies for childhood death under the age of five years?
According to the data compile by UNICEF, we see the following for the world:
1) Prematurity 18%
2) Pneumonia 14%
3) Birth Asphyxia 12%
4) Malaria 9%
5) Diarrhea 9%
6) Congenital anomolies 8%
7) Injuries 5%
8) Blood infections/sepsis 3%
9) Tuberculosis 3%
10) all others
From a global perspective, we are on the right track as deaths have decreased significantly from 12 million in 1990 to less than 5 million annually in 2022. This is a massive improvement in global childhood health. More work to be done as pneumonia and diarrhea based death should be less than 1%. Access to clean water, clean medicines and adequate medical care could crush these issues….plus a literature review as well as an ode to mothers.
Enjoy,
Dr. M

 

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 19

The Book that I never published. It is time for me to take another look at the mother child story in book form. In 2019, I embarked on a project of writing a book about maternal health and WHY it matters tremendously that we address the issues driving offspring dysregulation. The time since has ushered in an era of podcast guests that in some instances have solidified my beliefs on knowns while also shattering some beliefs leading to new ideas. Over the coming weeks, I am going to relook at this topic.
Part of this project is going to be taking a page out of the Derek Sivers’ book writing style, brevity and meaning are paramount. I am naturally hyper verbose and my writing style follows this reality. Thus, I am going to fight my natural style and desires in an effort to make this book shorter, much shorter and still powerful in delivery.
Here goes!
WHY?
The story of normal maternal health and how we are disrupting it in modern America…….Also a Literature review and recipe of the week!
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 16

Teenagers and tweens are a challenge to any parent as they embark on their identity development. These are years filled with angst, joy, love and pain, as our kids develop physically, mentally, and emotionally. As we attempt to guide but not control, we struggle watching them make and maybe repeat obvious mistakes. We, so dearly, want them to make the right choices (in our mind) and respect their bodies.
What can we do to help?
Dictating to teens will never work. They are more likely to sabotage their own lives in order to prove that they are in control. The tighter parents squeeze, the more the adolescent rebels.

I think of this stage of parenting as motivational interviewing…. and a literature review.

Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 14

Allergy Season and School – What is your plan?
Spring is coming and maybe even here already in Carolina. School is in full swing for kids and they are filled with joy and excitement. They are back outside enjoying sports and play. For the parents of allergy suffering kids, this is a time for check ups, medicines and the countless forms required by school. I know! What a pain!
The goal for parents and educators is to limit missed or unproductive school days due to asthma and allergies and to get the most out of the learning environment for all children. My goal is to help children be symptom free or as close as possible while also focusing on reducing mucous development which is a direct precursor to bacterial sinus and ear infections….and more
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #68 – John Warner, M.D. – Allergy, Milk and Prevention

This week we sit down with Dr.  John Warner, an Emeritus professor of Pediatrics at the Imperial College of London in the United Kingdom and also at the University of Cape Town in South Africa. We discuss his recent paper entitled: Strategies and Future Opportunities for the Prevention, Diagnosis, and Management of Cow Milk Allergy. Dr. Warner completed his undergraduate medical training in the School of Medicine, University of Sheffield and his initial pediatric experience was at the Children”s Hospital, Sheffield in the United Kingdom. He moved to London as Professor of Pediatrics and Head of Department at Imperial College St Mary’s hospital campus.  He is also Hon Professor of Pediatrics in the University of Cape Town.

In 2008 he became Director of Research for the Women and Children’s Clinical Programme Group, Imperial College Healthcare NHS Trust (ICHT). He was the lead for pediatrics in both the Biomedical Research Centre in ICHT and the NW London CLAHRC (Collaboration for Applied Health Research and Care) and was President of the Academic Pediatrics Association.

Professor Warner’s research has focused on the early life origins of asthma and related allergic and respiratory disorders.  He has published over 500 papers in scientific journals on these topics.  He was Editor in Chief of the journal Paediatric Allergy and Immunology from 1997-2010 and chairman of the paediatric section of the British Society for Allergy and Clinical Immunology for 5 years until 2010.  He was also a member of the Speciality and Training committee of the World Allergy Organisation and a past Trustee of the charity known as The Anaphylaxis Campaign. 

He was a member of the Advisory Committee for Novel Foods and Processes of the Food Standards Agency for 12 years until 2012 and was recognised for his work in food allergy research by the award of an OBE in 2013.

 

Please enjoy my conversation with Professor Warner,

Dr. M

 

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