Newsletter

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 9

Light and It’s Impacts on Health – Circadian Rhythms
Circadian comes from the latin Circa Diem or about the day
I have long believed that indoor sedentary behavior is profoundly bad for us beyond just the lack of movement and outdoor natural education. Today, we will look at another major concern: light. We will also get into a circadian rhythm post looking at Dr. Panda’s work. A final addition of a recipe of the week.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 8

Literature Review
1) Cancer is now a unique risk factor for Cardiovascular disease according to recent research. This is being discussed as a point of emphasis for those that have been diagnosed with cancer as the knowledge is a wake up alarm to the biological underpinnings of these disparate immune based diseases. (Melchiori R. et. al. 2023) If you have a strong family history of cancer and heart disease as I do, this data needs to be understood for a prevention lens focus. In a few weeksx I will be discussing APOE genotypes for understanding these realities.
2) In a translational model, sulphurophane increases mitochondrial biogenesis…..Plus a continuous glucose monitor experiment and more from Alison Gopnik’s book.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 7

This weeks podcast turned out to be so much more than expected when I first heard about Dr. David Clarke. His work transcends much of what I see in clinic and has given a name to the reality of puzzling chronic illness. From the PPDA website: Psychophysiologic disorders (PPD) are stress-related, brain-generated pain or illness. Even people who handle stress well can have PPD. This occurs when the stress is not fully recognized. The resulting symptoms are completely real. That is why the term we use is a blend of Psychology (the processes of the mind) and Physiology (the processes of the body)…..and a discussion on oral allergy syndrome.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 6

Literature Review
1) Psilocybin is showing further signs of great promise in the fight against depression and PTSD. Psychedelic assisted psychotherapy has gained a foothold in the mainstream of treatment interventions for treatment resistant depression and PTSD. Psilocybin comes from a mushroom that has serotonergic effects on the receptor 5HT2A in the human brain. The results of the studies were net positives in reducing major mood disorder symptoms that are known to be long term in effect. (Haikazian et. al. 2023) I am very excited to see this therapeutic space expand into traumatized teens and other subsets to see outcome benefits. 2) Nanoplastics in the research in the Journal PNAS….. And a section on Antibiotic resistance.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 5

Sugar, Immune Health and Two Studies
Let us start right out of the gate with two studies. #1: Here is the abstract from European Journal of Clinical Nutrition: “Milk contributes with saturated fat, but randomized controlled trials (RCT) on the effects of dairy on the risk of type 2 diabetes (T2D) where dairy is given as whole foods are scarce. The objective of our study was to investigate the long-term effects of semi-skimmed milk on insulin sensitivity and further to compare milk with sugar-sweetened soft drinks (SSSD). A secondary analysis of a 6-month RCT with 60 overweight and obese subjects randomly assigned to 1 L/d of either milk (1.5 g fat/100 mL), SSSD, non-calorie soft drink (NCSD), or water was conducted. Insulin sensitivity was evaluated by oral glucose tolerance test (OGTT) and plasma free fatty acids. Second, fasting blood lipids, blood pressure, and concentration of plasminogen activator inhibitor-1 were assessed……and more on antibiotic resistance.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 4

Literature Review
1) In an excellent paper by Dr. Harlan and colleagues, we see a group looking at how to modify ultra processed foods to remain tasty for consumption but also healthy. The lead author is Dr. Rob Lustig, a pioneering Pediatric Endocrinologist from UCSF and upcoming podcast guest. From the paper: “Ultraprocessed food is established as a metabolic disruptor acting to increase adiposity, reduce mitochondrial efficiency, drive insulin resistance, alter growth, and contribute to human morbidity and mortality. Consumer packaged goods (CPG) companies are beginning to understand the detrimental impact of the food they market, and have employed substitution strategies to reduce salt, sugar, and fat. However, the harms of ultraprocessed foods are far more complex than any single component, and are not ameliorated by such simple substitutions.” (Harlan et. al. 2023)……as well as information on Why ask why? and a recipe of the week.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 3

Resolutions? Do we need them?
The simple answer for me is this – if it causes beneficial change, then yes we need them. Ideally, change should occur real time as the need or knowledge of benefit becomes apparent.
New Years is traditionally a time that we introspect and set new goals for a better life. What that means to each one of us is as varied as the plants that exist, save for human health. We all WANT to be healthy. We all WANT to be happy. The impediment to being is not changing…..plus audience questions answered and a recipe of the week.
Enjoy,
Dr. M

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