Tag Archives: mitochondria

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 29

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Literature Review:
1) Is loneliness tied to an increase in death risk? A new study in Nature says yes to a degree of the pooled effect size of 1.32 for all cause mortality. (Wang et. al. 2023) In effect, that is a very large effect of the variable loneliness on death risk. Why would this be? Many reasons come to mind. The greatest of which is the control that our mind wields on our immune system. If we think in negative and in sad terms over a period of time, the immune system will shift into a pro inflammatory state and weakened pathogen killing which has massive downstream effects on physiology.
2) In an impressive inoculation study in the UK, researchers gave the ancestral strain of SARS2 to test subjects and then followed them for 2 weeks in quarantine……..
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Dr. M

Dr. M’s Women and Children First Podcast #47 – Terry Wahls, MD – Multiple Sclerosis and Healing

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This weeks guest is Dr. terry Wahls. Who is she?
From her website: Dr. Terry Wahls is a clinical professor of medicine at the University of Iowa where she conducts clinical multiple sclerosis trials . She is also a patient with secondary progressive multiple sclerosis, which confined her to a tilt-recline wheelchair for four years. Dr. Wahls restored her health using a diet and lifestyle program she designed specifically for her brain and now pedals her bike to work each day.
She is the author of The Wahls Protocol: How I Beat Progressive MS Using Paleo Principles and Functional Medicine, The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles, and the cookbook The Wahls Protocol Cooking for Life: The Revolutionary Modern Paleo Plan to Treat All Chronic Autoimmune Conditions.
She conducts clinical trials that test the effect of nutrition and lifestyle interventions to treat MS and other progressive health problems. Learn more about Dr. Wahls’ clinical trials here. She also teaches the public and medical community about the healing power of the Paleo diet and therapeutic lifestyle changes that restore health and vitality to our citizens. She hosts a Wahls Protocol Seminar every August where anyone can learn how to implement the Protocol with ease and success. Follow her on Facebook (Terry Wahls MD) and on Twitter at @TerryWahls.
For me, this is a story of revolution. The ability to stop a progressive disease and reverse it through upstream lifestyle trigger removal and the addition of substances known to fix defects in human biology. This is the story that we all need to look at from a prevention of all cause disease perspective. This is the how to not get sick over time starting at the earliest age of life.
Enjoy,
Dr. M

 

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 50

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The fundamentals are these: Age related changes that lead to neuronal loss and cognitive decline are related to loss or reduction of myokine release, systemic inflammation, insulin resistance, reactive oxygen induced mitochondrial stress, DNA mutations and poor protein intake.
First, exercise releases chemicals called myokines which are cell signaling molecules that have the job of telling other cells what to do via changes in gene expression, protein transcription and much more. The prototypical change is the increase of a substance called brain derived neurotrophic factor, BDNF, for short. BDNF is critical for brain cell mitochondrial biogenesis. BDNF promotes many developmental functions in the brain, including neuronal cell survival, differentiation, migration, dendritic arborization, and synaptic plasticity. Regular exercise promotes a progressive increase in BDNF protein for up to at least 3 mo………
Enjoy,
Dr.M