Tag Archives: insulin resistance

Dr. M’s Women and Children First Podcast #79 – Robert Lustig, MD – Obesity Epidemic

Welcome to the podcast! Today, I am thrilled to have a true pioneer in the field of metabolic health, Dr. Robert Lustig, MD, joining us. Dr. Lustig is a neuroendocrinologist and Professor Emeritus of Pediatrics in the Division of Endocrinology at the University of California, San Francisco. He is best known for his groundbreaking work on the intersection of diet, obesity, and metabolic disease, particularly his deep dive into the role of sugar as a driving force behind many of today’s chronic health issues.

As the author of several influential books, including Fat Chance, The Hacking of the American Mind and Metabolical, Dr. Lustig has been a vocal advocate for public health, helping to raise awareness about the harmful effects of processed foods, particularly refined sugars. His research has been instrumental in shifting the conversation around nutrition, focusing on the biological impacts of sugar and the ways it contributes to insulin resistance, obesity, and metabolic syndrome. His most recent paper entitled Obesogens, A Unifying Theory for the Global Rise in Obesity in the International Journal of Obesity – Nature is a ground stirring take on the current research.

We are excited to explore his latest insights into metabolic health and the science of obesity, and how we can apply this knowledge to improve our own well-being. Let’s welcome Dr. Lustig to the show!

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 50

The fundamentals are these: Age related changes that lead to neuronal loss and cognitive decline are related to loss or reduction of myokine release, systemic inflammation, insulin resistance, reactive oxygen induced mitochondrial stress, DNA mutations and poor protein intake.
First, exercise releases chemicals called myokines which are cell signaling molecules that have the job of telling other cells what to do via changes in gene expression, protein transcription and much more. The prototypical change is the increase of a substance called brain derived neurotrophic factor, BDNF, for short. BDNF is critical for brain cell mitochondrial biogenesis. BDNF promotes many developmental functions in the brain, including neuronal cell survival, differentiation, migration, dendritic arborization, and synaptic plasticity. Regular exercise promotes a progressive increase in BDNF protein for up to at least 3 mo………
Enjoy,
Dr.M

Insulin Resistance Tour with Dr. M

 

Have you ever wondered why we are struggling as a society to maintain health? This podcast is the place where you can start to understand the root cause or the headwaters of the disease river. Insulin resistance, in my mind is the root of the problem. The Answer to the dilemma is within these audio minutes for you to listen to at your leisure and at your pace to understand this complex topic distilled down into palatable bites.

 

Enjoy,

Dr. M