nutrition

Dr. M’s SPA Newsletter Volume 15 Issue 28 – Feeding Infants


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Food in Infancy
What do we know?

“Humans are the only mammals who feed our young special complementary foods before weaning and we are the only primates that wean our young before they can forage independently. There appears to be a sensitive period in the first several months of life when infants readily accept a wide variety of tastes and this period overlaps with a critical window for oral tolerance. As a result, infants should be exposed to a wide variety of flavors while mother is pregnant, while mother is nursing and beginning at an early age. There also appears to be a sensitive period between 4 and 9 months when infants are most receptive to different food textures. There remains debate about when it is best to begin introducing solid foods into an infant’s diet however, the available evidence suggests that provided the water and food supply are free of contamination, and the infant is provided adequate nutrition, there are no clear contraindications to feeding infants complementary foods at any age. There is emerging evidence that introduction of solid foods into an infant’s diet by 4 months may increase their willingness to eat a variety of fruits and vegetables later in life, decrease their risk of having feeding problems later in life, and decrease their risk of developing food allergies, and the early introduction of solid foods into an infant’s diet does not appear to increase their risk of obesity later in childhood.” (Borowitz S. 2021)

Food Introductions — What’s the best way to approach it?

As infants begin the shift from exclusive milk feeding to solid foods, a range of opinions inevitably emerge on how to navigate that transition. It’s tempting to get lost in modern guidelines, but an anthropological lens is often more revealing. Long before the age of purées in jars and puffed snacks in canisters, human infants ate what their parents ate. It was delivered in whole-food form and mechanically softened by chewing, cooking, or crushing. These early first foods carried important evolutionary advantages…Plus a piece on Hell Yeh or No by Derek Sivers

Enjoy,
Dr. M

Dr. M’s SPA Newsletter Volume 15 Issue 19

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For parents of special needs children, I honor you today.

I witness your strength every day in clinic.

You rise to meet challenges that many cannot begin to imagine, truly. You navigate medical appointments, therapy sessions, school meetings, and the unpredictable rhythms that come with raising a child with special needs.

Often without pause, without adequate rest, and without the recognition you deserve. For those single parents carrying this day to day reality, a double level of gratitude for you.

I want to pause for a moment and say what is too rarely said: you are extraordinary. Truly extraordinary.

Your love is not passive, it is an active force. It shows up at 2 AM when a child can’t sleep, in the quiet patience during a meltdown, in the persistence to advocate for services in a dysfunctional system requiring resilience summoned when the system says “no” but you know your child needs a “yes.”…. and a discussion of nutritional dark matter.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Volume 15 Issue 17

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Inflammaging from a Population View

In a landmark study published in Nature Aging on July 7, 2025, researchers challenge a cornerstone of modern gerontology by showing that inflammaging, chronic, age-associated low-grade inflammation, is not universal across all human populations. The abstract states the following: “Inflammaging, an age-associated increase in chronic inflammation, is considered a hallmark of aging. However, there is no consensus approach to measuring inflammaging based on circulating cytokines. Here we assessed whether an inflammaging axis detected in the Italian InCHIANTI dataset comprising 19 cytokines could be generalized to a different industrialized population (Singapore Longitudinal Aging Study) or to two indigenous, nonindustrialized populations: the Tsimane from the Bolivian Amazon and the Orang Asli from Peninsular Malaysia.

We assessed cytokine axis structure similarity and whether the inflammaging axis replicating the InCHIANTI result increased with age or was associated with health outcomes. The Singapore Longitudinal Aging Study was similar to InCHIANTI except for IL-6 and IL-1RA. The Tsimane and Orang Asli showed markedly different axis structures with little to no association with age and no association with age-related diseases. Inflammaging, as measured in this manner in these cohorts, thus appears to be largely a byproduct of industrialized lifestyles, with major variation across environments and populations.” (Franck et. al. 2025)

The research team analyzed 19 cytokines in over 2,800 individuals from four diverse populations: two industrialized cohorts: Italy’s InCHIANTI and the Singapore Longitudinal Aging Study (SLAS); two non-industrialized, Indigenous groups: the Tsimane of the Bolivian Amazon and the Orang Asli of Peninsular Malaysia.

In Italy and Singapore, the industrialized regions noted classic inflammaging signatures with inflammatory markers like IL‑6, TNF-α, and CRP increased with age, and correlated strongly with age-related chronic diseases such as cardiovascular and kidney disease….. and more on inflammaging…

Dr. M

Dr. M’s SPA Newsletter Volume 15 Issue 8

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Itaconate, what is it and why does it matter?

Science Heavy – skip to the bold for take home if you want to avoid the science.

The biggest takeaway from this complex science is this: High fat, high sugar diets (Ultra Processed Foods) are associated with decreased itaconate activity and increased inflammation. The science further answers the question of whether we should allow ultra processed food in schools.

Ultra Processed Foods likely reduce itaconate production driving inflammation, metabolic dysregulation, and gut dysbiosis, which could worsen active disease. Lower itaconate levels likely impair your body’s ability to resolve inflammation, potentially leading to prolonged issues with healing and repair. To support itaconate’s anti inflammatory activity, shift away from UPFs toward an anti-inflammatory diet (e.g., Mediterranean, rich in vegetables, omega-3s, and fiber) to reduce inflammation, support gut health, and enhance itaconate’s immune-regulating effects.

Science:…..

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast #90 – Kevin Boyd, DDS – Sugar, Oxygen and Neonatal Development

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Welcome to Dr. M’s Women and Children First Podcast, where we explore groundbreaking approaches to health and wellness for women and children. Today, we’re honored to introduce Dr. Kevin Boyd, DDS, MSc, a board-certified pediatric dentist and a trailblazer in the field of evolutionary oral medicine. With an illustrious career spanning over three decades, Dr. Boyd practices in Chicago and serves as an attending instructor at Lurie Children’s Hospital’s Pediatric Dentistry Residency Program, where he also consults for the Sleep Medicine service.

Dr. Boyd’s unique perspective is rooted in his undergraduate work in Biological Anthropology at Northeastern University as well as a Masters of science in Human Nutrition and Dietetics from Michigan State University.

As a Visiting Scholar at the University of Pennsylvania’s Museum of Anthropology, he conducts pioneering research into how dietary and lifestyle changes since the Industrial Revolution have impacted craniofacial and respiratory development. His work in Darwinian Dentistry draws on anthropological insights, examining prehistoric fossil records to understand modern systemic diseases, particularly those affecting airway health in children.

A passionate advocate for early intervention, Dr. Boyd focuses on preventing and treating craniofacial-respiratory issues in young children, often under age 7, to promote healthy breathing, sleep, and neurocognitive development. Through his global lectures on early childhood malocclusion, pediatric sleep-breathing hygiene, and evolutionary oral medicine, Dr. Boyd is educating clinicians and parents alike.

Join us as Dr. Boyd shares his anthropological insights, clinical expertise, and vision for revolutionizing airway health to help women and children thrive. Let’s dive in!

Dr. M

Dr. M’s Women and Children First Podcast #14 Repost- Richard Johnson MD – Nature Wants Us to Be Fat

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This is a repost of the most listened to podcast with Richard J. Johnson, M.D.. Dr. Johnson is the Tomas Berl Professor of Medicine and the Chief of the Renal Division and Hypertension at the University of Colorado since 2008. A graduate of the University of Wisconsin, Madison, with a major in Anthropology, and a graduate of the University of Minnesota Medical School, Minneapolis, he is a physician and nephrologist whose research has focused on the role of sugar, and especially fructose, in driving obesity, diabetes, high blood pressure and kidney disease. Much of this work has explored the role of fructose metabolism, especially the generation of uric acid, in driving this phenotype, and his work has included studies ranging from molecular biology, integrative physiology, and evolutionary biology. He is the author of The Sugar Fix which introduced the first low fructose diet, and also The Fat Switch which explores the role of fructose in driving the obesity epidemic. His newest book, Nature Wants Us To Be Fat, is a tour de force of the entire pathway of survival via metabolic events in the body related to fructose and the polyol pathway. This is a must read book. This podcast will introduce you to the exceptional work of Dr. Johnson and how we are now mismatched metabolically for the environment of modern America and our food systems.

Please enjoy this wide ranging conversation.

Dr. M

Dr. M’s Women and Children First Podcast #85 – Lily Nichols RD

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Welcome back to Dr. M’s Women and Children First Podcast, where we dive deep into the latest research and expert insights on health, nutrition, and optimizing well-being. Today, we sit down with an influential voice in prenatal and fertility nutrition, Lily Nichols, RD.

Lily is a registered dietitian, researcher, and best-selling author known for her groundbreaking work on real food nutrition for pregnancy. Her previous books, Real Food for Pregnancy and Real Food for Gestational Diabetes, have redefined how we think about maternal nutrition, blending ancestral wisdom with cutting-edge science. Now, with her latest book, Real Food for Fertility, she expands her expertise to help couples optimize their chances of conception and support a healthy pregnancy from the very start.

In this conversation, we’ll explore the critical role of nutrient-dense, whole foods in fertility, how conventional dietary advice may be missing key elements, and why blood sugar balance, gut health, and micronutrient status are essential for reproductive success. Lily’s research-driven approach challenges outdated dogma and offers practical, evidence-based solutions that can make a real impact on fertility outcomes.

Whether you’re planning for pregnancy, supporting a loved one on their journey, or simply interested in how diet shapes reproductive health, this episode is packed with actionable takeaways.

Join me in welcoming Lily Nichols, RD, to the podcast!

Dr. M

Real Food for Fertility

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