Newsletter

Dr. M’s SPA Newsletter Volume 15 Issue 1

Some Key Literature Review Studies from Year 14

This is a bit of a long newsletter. That is intentional. This will be a repository for some of the best research for us to look back on from time to time this coming year to solidify the learning moving forward.

1) Time restricted eating patterns are known to help physiology and metabolism by initiating a pause in the action of mTOR and muscle synthesis as well as inducing autophagy. Autophagy is critical to the clearance of broken or damaged cells following injury or disease…..Plus a to do list and recipe of the week.

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 52

Here are 20 takeaways from year 14 of the SPA Newsletter

1) Diet significantly impacts respiratory health – Reducing processed foods and increasing anti-inflammatory nutrients can help manage asthma and allergies.

2) Consistent sleep routines improve cognitive function – Children who maintain a regular sleep schedule have better emotional regulation, learning capacity, and immune health.

3) Environmental toxins affect child development – Reducing exposure to air pollutants, pesticides, and household chemicals lowers the risk of chronic illnesses and delayed learning.

4) Chronic stress in children is rising – Teaching mindfulness, outdoor play, and limiting academic overburden will support mental well-being. Over stressing a child leads to little in the positive realm. Align their learning with their passions and watch them thrive.

5) Processed foods are linked to behavior issues among so many issues – High sugar and ultra-processed diets may contribute to ADHD-like symptoms and mood instability…..

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 51

Here is an article that I wrote for Rupa Fullscript in order to lay the ground work for effective preventative medicine. In order to get a longer runway to preventing disease, targeted lab screening is becoming very important.

Classical medical training often relies on a traditional, binary approach to patient care: either a disease is present, or it is not. Functional medicine builds on this perspective by examining a continuum of potential dysfunction within lab results. Rather than waiting for a definitive diagnosis, functional medicine practitioners look for subtle “breadcrumbs” in the data—early indicators that might signal an evolving health issue long before it fully manifests. Routine lab panels remain a foundational tool, but their deeper insights are frequently underutilized. In functional medicine, we dig into each lab marker more thoroughly, considering it a potential clue to underlying imbalances, nutrient deficiencies, or early disease processes. This more granular interpretation goes beyond the standard understanding of “normal” values, seeking patterns that can inform more personalized and preventive care.

By viewing “normal” lab ranges through a more nuanced lens, functional medicine aims to identify previously overlooked indicators. The ultimate goal is to narrow our concept of “optimal” health ranges, enabling a more attentive and individualized approach that supports the patient’s best possible health outcomes…..plus a section on literature reviews.

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 50

“Life forms on our planet have evolved under the strong influence of a daily light/dark cycle. Sunlight being the primary source of energy for photosynthesis, the daily production of photosynthetic biomass has a predictable diurnal rhythm. The daily cyclical production of photosynthesized chemical energy is at the base of the food chain. Daily changes in light and darkness result in diurnal rhythms in other environmental parameters such as temperature and humidity. Such a predictable and robust daily rhythm in food availability and environmental factors has led to the evolution of a ~24 h internal timing mechanism or circadian rhythm to enable organisms to anticipate daily changes and to optimize fitness. Fundamental to this 24 h rhythms is the ability to acquire food when it is available and to store a portion of these resources for utilization during the rest of the day (i.e. the fasting period) without compromising fitness and vitality. The fasting period also serves as a time for standby and repair so that the organism is fit and competent to harvest energy when light (for photosynthetic organisms) or food becomes available. While many non-photosynthetic lifeforms with short lifespan (< a few days) may not derive profound benefit from a circadian timing system, they share fundamental biochemical mechanisms for acquiring and storing food when it is available and then utilizing this stored energy during a quiescent period of fasting for repair, stress resistance and vitality.” (Longo et. al. 2016)

This is the crux of the understanding that we, the homo sapiens on Earth, need to realize that biology trumps any desire that we may have to fight against it. We are and have been moving in the wrong direction for quite some time as it relates to what we were meant to do biologically as children and then adults. Not coordinating activity with the sun is a negative recipe for health. Third shift workers are the canary’s in the coal mine for the risks of working and being awake when the sun is down and sleeping when it is up. This population has some very high risks for metabolic disease based on the data. (Biggi et. al. 2008)

Plus a section on filaggrin genes and skin function.

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 49

Over the next few weeks, I will be doing a deeper dive into the world of eczema or atopic dermatitis. In the greek language where we derive many of our medical terms, eczema is spelled ἔκζεμα or ékzema which means to bubble up. This weeks podcast guest is Dr. Ana Maria Temple, an expert in eczema. We go all over the place in the pod and it is so worth your time if your child suffers from eczema.

Eczema is a multifactorial skin condition that affects millions worldwide, manifesting as red, itchy rash due to inflamed skin. Its prevalence has been steadily rising, particularly in industrialized nations, which suggests a complex interplay of genetics, environmental factors (epigenetics), and immune dysregulation. As we unpack the root causes of eczema over the coming weeks, an integrative functional medicine approach highlights not only the “what” but the “why” behind this condition—providing opportunities for both prevention and healthier management…..plus a section on Skin pH.

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 48

Holidays and Connection

The Christmas and winter holiday season is a unique time to sit back reflect on the past year. To behold the timeless beauty of life. The shared time offers us an opportunity to pause and connect with those who matter or should matter most in our lives. I love the bathroom plaque that says at the end of life it won’t matter what you owned or what you knew, but rather the impact you had in a child’s life. Fortunately, for us, the holidays bring a chance to foster authentic human connections. To actually sit in conspiracy together. These moments are more than just traditions, they are essential for our emotional, mental, and even physical health. In the hustle of modern existence, where schedules dominate and technology often mediates relationships, we are losing this skill set, especially for the younger generations, making it more important to stay focused now.

Let us define human connection: Human connection is the act or feeling of being seen, heard, cared for and valued by another person or group. It is a most primary need for humans starting in infancy when a child needs a mother’s touch and milk. It arises from the countless meaningful interactions that foster mutual understanding, trust, empathy, and shared emotional experiences that ultimately lead to a child’s feeling of safety. The critical time period to establish attachment and connection is the first 2 to 3 years of life. Plus a section of literature review and a recipe of the week.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 47

Sulfurophane and health – It is clear now that SFN stands out as a powerhouse phytochemical with profound effects on human health through the pathway of nurclear factor erythroid related 2 (NRF2). It is found abundantly in cruciferous vegetables such as broccoli, broccolini, kale, and brussels sprouts. SFN is a bioactive compound with impressive clinical potential for preventing chronic disease and optimizing cellular health, especially in oxidant impaired/overloaded states. At its core, SFN is a sulfur-rich molecule derived from glucoraphanin, a glucosinolate precursor. The transformation occurs when the enzyme myrosinase, released during the chopping or chewing of cruciferous vegetables, catalyzes the reaction. Interestingly, this enzymatic activation can also be achieved via gut microbiota when raw vegetables are absent from the diet, emphasizing the remarkable adaptability of our biology to source essential nutrients as needed for survival. (Ali et. al. 2023)

Nrf2 is a master regulator of cellular defense, orchestrating the production of detoxification enzymes, antioxidants, and other cytoprotective proteins. By activating Nrf2, sulforaphane enhances the body’s resilience to oxidative stress, a key contributor to aging, inflammation, and the development of chronic diseases such as cardiovascular disease and diabetes. Studies reveal that sulforaphane also induces Phase II detoxification enzymes, such as glutathione S-transferase, which play a vital role in neutralizing and excreting harmful toxins.