Dr. M’s Women and Children First Podcast #71 – Steve Hodges, M.D., Ph.D. – Bedwetting and Constipation

Enuresis, Encopresis and Constipation
This week I sit down with Dr. Steve Hodges to discuss bedwetting, constipation and more.
Dr. Steve Hodges is a Urological surgeon and expert in the field of enuresis, encopresis and child urological health. He received his BA in classical and ancient studies from Duke University before completing medical school and residency at Wake Forest University in North Carolina. He completed further Pediatric fellowships in Urology at the University of San Diego and again at Wake Forest. From there his career is one of exploration, questioning and seeking new answers to old questions. He has authored multiple books including It’s No Accident, Emma and the E Club: An Epic Episode About Eliminating Enuresis and Encopresis, and the MOP book anthology. He is widely published in top Urological Journals.
Today we sit down to dissect the issues of enuresis(Bedwetting), encopresis (self stooling) and chronic constipation. The exploration is exactly what we need, root cause analysis and treatments based on the reasons not the symptoms.
Please enjoy my conversation with Steve Hodges,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 18

Unraveling the Mysteries of the Amygdala: A review of a section of the book Behave by Robert Sapolsky
In the world of neuroscience, Robert Sapolsky stands as a luminary, a maestro of unraveling the intricate dance of our brain’s circuitry. Among the many deep dives that he delves into, his perspective on the amygdala resonates profoundly for me. The amygdala emerges not as a mere anatomical curiosity as he decides that rather than reducing the amygdala to a simplistic seat of fear and aggression, he highlights its diverse functions, emphasizing its involvement in the vast array of behaviors and experiences. It is a narrative view of the why the brain developed as it did to aid us in the fight against pathogens, predators and stress. Sapolsky’s take on the amygdala is nothing short of revelatory, akin to a seasoned detective peeling away layers of a perplexing case. There are diverse neuronal pathways in this almond-shaped structure nestled deep within our temporal lobes and they have profound purpose. The amygdala emerges not merely as a primal seat of fear and aggression, but as a nuanced orchestrator of our emotional lives. All mammals have emotional responses that are split second to threat, joy and relationship. This is mediated……Plus a section on DNA and memory. Finally, a recipe.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 17

Literature Review
1) In a first of its kind study in mice, we see concrete evidence for how the mitochondria in obese individuals are a root cause of disease based on nutritional input. This fascinating animal translational study gives us insight into how a high fat diet is also a major component of mitochondrial damage through fission and fragmentation leading to worsened cell bioenergetics. The cells have reduced fatty acid oxidation or fat burning capacity due to a single gene’s actions. The end result is a tilt toward fat cell production, fat storage and fat cell inflammation which are associated with diabetes and insulin resistance and ultimately metabolic syndrome. This starts to explain the paradox that is obesity where the person has a ton of stored energy, but has limited capacity to utilize it. It is like having a gas tank of fuel with a gas line that only allows for 1/10th of the flow required for optimal function. Science Daily has an excellent review of this paper. Link below. 
2) Women’s brains change during pregnancy as per a new study. The authors looked at brain changes before and after birth as well as with or without a vaginal delivery route. Their study findings noted transient changes in some brain regions as well as permanent changes in other brain regions that turn on self-reflection and empathy for others…… and a recipe of the week.
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #70 – Stan Gabryszewski, M.D., Ph.D. – Allergies

This week I sit down with Dr. Stan Gabryszewski to discuss allergies from multiple angles.
Dr. Gabryszewski graduated from Princeton University with a degree in Molecular Biology before attending Columbia University for his MD as well as a PhD degree in Cellular, Molecular and Biomedical Studies. He then completed his pediatric residency and is a senior allergy immunology fellow at the Children’s Hospital of Philadelphia where he now teaches and performs research in the lab of Dr. David Hall. His research is focused on better understanding the epidemiologic and immunologic features among pediatric allergic disorders, in particular the food allergies IgE-mediated food allergy and eosinophilic esophagitis.
In this conversation, Stan and I sit down to discuss his recent paper in Pediatrics entitled, Patterns in the Development of Pediatric Allergy. This article is a much needed look at the true prevalence of allergy and allergic diseases in children. We discuss the statistics as well as the thoughts behind the why this is occurring. The upstream reasons are very important, hard to tease out but worthy of discussion.
Please enjoy my conversation with Stan Gabryszewski,
Dr. M
His recent paper in pediatrics.

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 16

Teenagers and tweens are a challenge to any parent as they embark on their identity development. These are years filled with angst, joy, love and pain, as our kids develop physically, mentally, and emotionally. As we attempt to guide but not control, we struggle watching them make and maybe repeat obvious mistakes. We, so dearly, want them to make the right choices (in our mind) and respect their bodies.
What can we do to help?
Dictating to teens will never work. They are more likely to sabotage their own lives in order to prove that they are in control. The tighter parents squeeze, the more the adolescent rebels.

I think of this stage of parenting as motivational interviewing…. and a literature review.

Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 15

Micro/nano-plastics (MNP) – the new ultra threat to our health
In a first of its kind study, a group out of Italy has found quite disturbing results in the hearts of a few hundred tested individuals. From the study: 257 patients completed a 35 month study where they detected polyethylene in the 59% of the patient’s heart’s carotid artery plaque. In addition, 12% of the patients had detectable amounts of polyvinyl chloride. “Electron microscopy revealed visible, jagged-edged foreign particles among plaque macrophages and scattered in the external debris. Radiographic examination showed that some of these particles included chlorine.” (Marfella et. al. 2024) Individuals with micro/nanoplastics in the carotid atheroma were at significantly higher risk for myocardial infarction, stroke, or death than those without detectable MNP. The hazard ratio is 4.5 which is to say that the risk is 4.5 X higher for the plastic exposed people…..plus a literature review.
Enjoy,
Dr. M

Dr. M’s Women and Children First Podcast #69 – Stephen Porges, Ph.D. – Polyvagal Theory

This week I sit down with Dr. Stephen Porges,
He is a Distinguished University Scientist at Indiana University where he is the founding director of the Traumatic Stress Research Consortium. He is Professor of Psychiatry at the University of North Carolina, and Professor Emeritus at both the University of Illinois at Chicago and the University of Maryland.
He served as president of the Society for Psychophysiological Research and the Federation of Associations in Behavioral & Brain Sciences and is a former recipient of a National Institute of Mental Health Research Scientist Development Award. He has published more than 400 peer-reviewed papers across several disciplines including anesthesiology, biomedical engineering, critical care medicine, ergonomics, exercise physiology, gerontology, neurology, neuroscience, obstetrics, pediatrics, psychiatry, psychology, psychometrics, space medicine, and substance abuse. In 1994 he proposed the Polyvagal Theory, a theory that links the evolution of the mammalian autonomic nervous system to social behavior and emphasizes the importance of physiological state in the expression of behavioral problems and psychiatric disorders. The theory is leading to innovative treatments based on insights into the mechanisms mediating symptoms observed in several behavioral, psychiatric, and physical disorders.
He is the author of multiple books on his Polyvagal Theory: including the Neurophysiological foundations of Emotions, Attachment, Communication, and Self-regulation, as well as Polyvagal Safety: Attachment, Communication, Self-Regulation. His newest book cowritten with his son is called Our Polyvagal World, How Safety and Trauma Change Us. Dr. Porges is the creator of a music-based intervention, the Safe and Sound Protocol ™ (SSP), which is used by therapists to improve social engagement, language processing, and state regulation, as well as to reduce hearing sensitivities.
This is such a fascinating conversation. He brings the worlds of psychiatry and anthropological physiology into union for us to understand the why of trauma reactions and the future unwinding that is now possible. This is a must listen to conversation if you know anyone with trauma history.
Please enjoy my conversation with Professor Porges,
Dr. M
His recent paper in Frontiers in Integrative Neuroscience
Website for Dr. Porges
Newest Book – Our Polyvagal World

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