Virus

Dr. M’s Women and Children First Podcast #27 – Dr. Paul Offit – Covid Vaccines

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Dr. Paul A. Offit is Director of the Vaccine Education Center and professor of pediatrics in the Division of Infectious Diseases at Children’s Hospital of Philadelphia. He is the Maurice R. Hilleman Professor of Vaccinology at the Perelman School of Medicine at the University of Pennsylvania.

Dr. Offit is an internationally recognized expert in the fields of virology and immunology, and was a member of the Advisory Committee on Immunization Practices to the Centers for Disease Control and Prevention. He is a member of the Food and Drug Administration Vaccines and Related Biological Products Advisory Committee, a member of the Institute of Medicine and co-editor of the foremost vaccine text, Vaccines.

He is a scientist, a skeptic, a thinker and an individual deeply passionate about children’s health.

This week we sit down to discuss Covid, vaccines and children’s health.

I hope that you enjoy my conversation with Dr. Offit,

 

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 24

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A subset of children may be more susceptible to respiratory infections of viral and bacterial varieties based on some new research. It appears that the microbiomes of the nasopharyngeal respiratory tract and host immune defenses play a major role here. We discuss some new research regarding infection risk. We also discuss snakes, post bite care and avoidance.

More to learn,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issues 21/23, Covid Updates 61/62

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Coronavirus Update #61 and 62 – This audiocast newsletter looks further into the new variants and other emerging data sets. More information on boosters, infection risks and opinions from Paul Offit and Monika Gandhi. Plus a look at Adenoviral hepatitis and formula issues.

 

Enjoy,

Dr. M

Dr. M’s Women and Children First Podcast – Omicron Update

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COVID Omicron Update:
There is a ton of interesting information flying around about Omicron and the pandemic in general. Today, I breakdown the new variant and what we know overall. It is time to get the facts out there and not just the case volume hype.
COVID Omicron Update: Let’s breakdown the new variant and what we know overall.We need a new look at this situation. The world according to SARS2 Covid 19 Delta is changing to a newer Omicron reality. What does this mean?
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 11 Issues 37 Covid Update #43

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Delta is a pain in the BUTT, but our T and B cells are ready to wage war once we have either had natural infection or received the SARS2 vaccine.
Evolution of the SARS2 coronavirus may have reached a perfect level of fitness with the delta variant. It is incredibly effective at transmission while not being more deadly than alpha. Time will ultimately tell if it evolves again in a significant way. If you think of the evolution of humanity with respect to SARS2/Covid19 risk, it is clear to me that this virus would have been much less deadly 30 or 50 or 100 years ago before the invention of modern processed foods, chemicals and stress that have upended human immune health and lead to an era of metabolic diseases and disease. I have thought about this for some time and the reality is as such. We are here to some extent by our own doing and that is a tragedy of our time.
Some may say that modern medicine is saving countless lives and that is so, but how many would have never entered the hospital based on much better baseline health? Ah, these are questions that we cannot answer less we just hypothesize.
Read more for COVID #43….https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 11 Issues 33 and 35 Covid Update #41/42

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A few people are asking about the need to vaccinate if you have already had COVID natural illness. What is the story here? Hot off of the press from Cell Reports Medicine, we see: “Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based immune responses. SARS-CoV-2 spike binding and neutralizing antibodies exhibit a bi-phasic decay with an extended half-life of >200 days suggesting the generation of longer-lived plasma cells. SARS-CoV-2 infection also boosts antibody titers to SARS-CoV-1 and common betacoronaviruses. In addition, spike-specific IgG+ memory B cells persist, which bodes well for a rapid antibody response upon virus re-exposure or vaccination. Virus-specific CD4+ and CD8+ T cells are polyfunctional and maintained with an estimated half-life of 200 days. Interestingly, CD4+ T cell responses equally target several SARS-CoV-2 proteins, whereas the CD8+ T cell responses preferentially target the nucleoprotein, highlighting the potential importance of including the nucleoprotein in future vaccines. Taken together, these results suggest that broad and effective immunity may persist long-term in recovered COVID-19 patients.” (Cohen et. al. 2021)

Read more for COVID #41……https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter/988-volume-11-letter-33-coronavirus-update-42

Read more for COVID #42……https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter/994-coronavirus-update-42

Happy listening

Dr. M

Dr. M’s SPA Newsletter Volume 11 Issue 27 Covid Update #38

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Just when you think that the information on SARS2 Covid19 is slowing to a crawl with new discovery, a favorite researcher publishes a truly remarkable bit of scientific discovery. Dr. Alessio Fasano is featured below in Number 6 and his work is really important. A little science heavy but critical for children. There is a take home summary as well. Don’t miss this information.
Quick hits
1) CDC data on adolescent hospitalizations: COVID-19 adolescent hospitalization rates from COVID-NET peaked at 2.1 per 100,000 in early January 2021, declined to 0.6 in mid-March, and rose to 1.3 in April. Among hospitalized adolescents, nearly one third required intensive care unit admission, and 5% required invasive mechanical ventilation; no associated deaths occurred….. Read more at this link: https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter/964-volume-11-letter-27-coronavirus-update-38

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