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Coronavirus Update #39 Quick hits
1) Repeat with new information as an important follow up on MIS-C, multi inflammatory syndrome – c., from 2 weeks ago. Remember that in children, MIS-c is associated with poor intestinal function from a microbiome perspective coupled to genetic weaknesses in immune suppression of chemokine CXCL9 post inflammation. Research from the lab of Dr. Alessio Fasano has shown direct evidence of intestinal permeability in children with multi inflammatory syndrome – c:
The authors found that children, unlike adults, the SARS2 virus decides to take up residence in the intestines and replicate there. The virus can be found in the child’s stool via testing. This is a unique finding to children as the intestine is not known to be a harboring site for the virus in adults. The expert researcher on this paper, Dr. Fasano, has extensive knowledge of the function of the intestinal mucosal lining and the fact that the cells are held together by tight junctions made up of different proteins forming a semi impermeable membrane…….
Read more at https://www.salisburypediatrics.com/patient-education/dr-magryta-s-newsletter
Have a great day,
Dr. M
