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Dr. M’s SPA Newsletter Volume 15 Issue Thanksgiving


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THANKSGIVING THOUGHTS

Every year, as the leaves turn and the air gets that crisp bite, I’m pulled back to 1621 in Plymouth, Massachusetts where a group of English Pilgrims, religious refugees who had crossed an ocean to breathe free, and their Wampanoag neighbors sat down together for three days of feasting. No treaties, no agendas, just gratitude for a successful harvest and the simple miracle that two very different peoples could share a meal in peace. Food and friendship. That was the entire point. At least, that is what history tells us.

Fast-forward two centuries and Abraham Lincoln, in the middle of the bloodiest war this country has ever known, paused on October 3, 1863 to proclaim a national day of Thanksgiving.

His words still ring true: “The year that is drawing towards its close, has been filled with the blessings of fruitful fields and healthful skies. To these bounties, which are so constantly enjoyed that we are prone to forget the source from which they come, others have been added, which are of so extraordinary a nature, that they cannot fail to penetrate and soften even the heart which is habitually insensible to the ever watchful providence of Almighty God….

Dr. M

Dr. M’s SPA Newsletter Volume 15 Issue 27 – Immune Aging

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The Evolutionary Tug-of-War – Inflammation’s Double-Edged Sword

“Environmental factors, particularly infections, have fundamentally shaped human evolution by selecting for protective inflammatory response mechanisms that enhance survival. This evolutionary pressure has created a core biological paradox: inflammation is indispensable for host defense, yet its dysregulation significantly heightens disease and mortality risk. This fundamental tension raises three fundamental questions about human aging and immunity: (1) How have selective pressures driven the evolution of mechanisms to balance inflammation’s protective benefits against its harmful consequences? (2) Why does substantial variability in healthspan persist despite historically stable rates of aging? (3) Does evolutionary prioritization of reproductive fitness inherently limit longevity?” (Manoharan et. al. 2025)

Let’s talk about the fire inside us. Inflammation is our body’s 911 system: lightning-fast, life-saving when a bug invades or a thorn rips skin. But leave that alarm blaring 24/7 and the fire torches the house.

Evolution faced this paradox: crank the immune dial high enough to survive infection and childbirth, yet install brakes so we don’t self-destruct by 40. Manoharan’s team just mapped those brakes in 17,500 humans and called it immune resilience (IR) or the ability to fight hard, clean up fast, and stay cool afterward… and linguistic aging associations…

Dr. M

Dr. M’s SPA Newsletter Volume 15 Issue 26 – Back To Sleep

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Back to Sleep and Sudden Infant Death Syndrome (SIDS)

Sudden Infant Death Syndrome (SIDS) is defined as “the sudden death of an infant under one year of age which remains unexplained after a thorough case investigation, including a complete autopsy, examination of the death scene, and review of the clinical history.”

During my time at the University of Virginia, I trained under neonatologist Dr. John Kattwinkel, a champion for newborn health and one of the leading figures in shaping national safe sleep policies. In the early 1990s, he chaired the American Academy of Pediatrics (AAP) Task Force on Infant Sleep Position and SIDS, which laid the foundation for the landmark Back to Sleep campaign.

At that time, SIDS claimed roughly 14 infants per 10,000 live births in 1988. Following the campaign’s launch in 1994, the rate plummeted by over 60%, reaching about 5 deaths per 10,000 live births by 2006. Despite this dramatic improvement, recent data suggest that the decline has plateaued…..

Dr. M

Dr. M’s SPA Newsletter Volume 15 Issue 25 – Tough Conversations

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Speaking Truth in Love: The Weight of Avoidance in Pediatric Metabolic Health

After completing the second round of our Asthma and Obesity Metabolic Pilot Program at Salisbury Pediatrics, I left the clinic reflecting deeply on what I witnessed. It crystallized a truth that is uncomfortable but undeniable: the greatest health threats to our children today are not infectious or accidental, they are metabolic. Diseases once reserved for adulthood: insulin resistance, fatty liver, hypertension, early vascular aging are now appearing in children who should be free to run, play, and thrive.

In modern society, conversations about weight and metabolic dysfunction have become relatively taboo. This is not to say that children of normal or low weight are immune; they, too, can be at risk. However, the excess-weight group carries the highest statistical burden. Too often, clinicians hesitate to speak truth to families for fear of offending, shaming, or overstepping. In doing so, we risk silence becoming complicity and allowing preventable disease to take root in the very children we are charged to protect.

Much of this epidemic is not born of individual failure but of systemic neglect. Government-funded, poor-quality school meals, cheap processed foods, and relentless marketing of sugar and refined carbohydrates have built an environment where metabolic injury is almost inevitable. When a child’s daily fuel is engineered for shelf life instead of cell life, the outcome is not accidental, it is predictable. Our pilot program lab results are a painful window into that truth…. and a literature review on eczema and anaphylaxis.

Enjoy Dr. M

Dr. M’s SPA Newsletter Volume 15 Issue 22/23/24 – Acetaminophen and Autism

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Review Part III – after the Attia Podcast

After completing the interview with Dr. William Parker and now listening to Peter Attia’s analysis, let us look again at this question. I repeat that the initial question has not changed for me. The first and most fundamental question to ask is this: What is the true value of acetaminophen in health compared with the potential risk if the associated findings are indeed correct?

My response to this question has been altered by the analysis so far.

I love this from Dr. Attia: “Some people might be wondering, why did you just take so long to explain all this to us? Why don’t you just give us the answer? I just want the sound bite, man

Peter’s reply, “If you just want sound bites, you’re never going to learn.”

Honestly, if you just want sound bites, this isn’t the podcast for you. But if you actually want to be able to learn to think for yourself, then that’s what we’re here to do. And that’s the reason we killed ourselves over the past week to put together the most thorough gathering of all the data we could find and the most intense night-weekend analysis possible. “

I agree! I believe that the science and data are key. So here goes – round three!…..

Dr. M

 

Dr. M’s SPA Newsletter Volume 15 Issue 20/21

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Flu season is around the corner and we should take a look at the virus for preparation purposes.

Influenza

Every few years, I revisit this virus in my writing, not only to keep it on your radar in preparation, but also because of the significant illness and death it continues to cause. It’s never wise to dismiss its potential impact. Influenza reliably returns each year, difficult to escape even with strict isolation.

The flu is different from the common cold in many ways as the flu has:

1) Rapid onset with high spiking fevers

2) Muscle and headaches

3) Little to not sneezing and sore throat

4) Rapid and robust cough onset

Influenza season is beginning in the United States this fall. Who gets sick? In short, people of all ages. Seasonal influenza has a reproductive rate of just over one, meaning that each infected person typically spreads the virus to one or two others through coughing or sneezing in close proximity. The virus also survives on surfaces for up to 24 hours, creating another common route of transmission, especially in children. Young kids frequently touch surfaces and each other, then touch their faces, providing the perfect pathway for infection. Because of this, schools remain a major hub for flu transmission across the country.

Preventing the virus from taking root in your body is the key to avoiding a bad outcome.

Things that I think of as critical to avoiding or preventing this infection:

1) Keeping your vitamin D level greater than 50 ng/ml is an important way to prevent influenza infections. Get tested and supplement accordingly. As always the sun is your natural route to normal D levels

2) Get adequate sleep based on your age to keep your immune system in great shape. Sleep is very important for immune health…… and more on asthma driving mental health issues.
Dr. M

Dr. M’s SPA Newsletter Volume 15 Issue 19

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For parents of special needs children, I honor you today.

I witness your strength every day in clinic.

You rise to meet challenges that many cannot begin to imagine, truly. You navigate medical appointments, therapy sessions, school meetings, and the unpredictable rhythms that come with raising a child with special needs.

Often without pause, without adequate rest, and without the recognition you deserve. For those single parents carrying this day to day reality, a double level of gratitude for you.

I want to pause for a moment and say what is too rarely said: you are extraordinary. Truly extraordinary.

Your love is not passive, it is an active force. It shows up at 2 AM when a child can’t sleep, in the quiet patience during a meltdown, in the persistence to advocate for services in a dysfunctional system requiring resilience summoned when the system says “no” but you know your child needs a “yes.”…. and a discussion of nutritional dark matter.

Enjoy,

Dr. M

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