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Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 20

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“It is your reaction to an adversity not the adversity itself that determines how your life’s story develops.”
Dieter Uchtdorf
WHY?
What are the Underpinnings of Disease?
What have we really learned over the last one to two hundred years of medicine?
We left an era where infections killed the majority of children and adults, especially during childbirth and the first 5 years of life. Science gave us antimicrobial medicines and vaccines that altered this landscape and humans began to live decades longer.
Medicine had conquered disease. However, it was not so. Insidiously, these victories were met with new problems called diseases of aging – heart disease, asthma, autoimmunity, diabetes, cancer, obesity, dementia and others…… and a literature review.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 17

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Literature Review
1) In a first of its kind study in mice, we see concrete evidence for how the mitochondria in obese individuals are a root cause of disease based on nutritional input. This fascinating animal translational study gives us insight into how a high fat diet is also a major component of mitochondrial damage through fission and fragmentation leading to worsened cell bioenergetics. The cells have reduced fatty acid oxidation or fat burning capacity due to a single gene’s actions. The end result is a tilt toward fat cell production, fat storage and fat cell inflammation which are associated with diabetes and insulin resistance and ultimately metabolic syndrome. This starts to explain the paradox that is obesity where the person has a ton of stored energy, but has limited capacity to utilize it. It is like having a gas tank of fuel with a gas line that only allows for 1/10th of the flow required for optimal function. Science Daily has an excellent review of this paper. Link below. 
2) Women’s brains change during pregnancy as per a new study. The authors looked at brain changes before and after birth as well as with or without a vaginal delivery route. Their study findings noted transient changes in some brain regions as well as permanent changes in other brain regions that turn on self-reflection and empathy for others…… and a recipe of the week.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 12

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Pregnancy is a super important time. Do not take by inhalation, ingestion or other exposure anything that is a potential toxin for the body.
Things to avoid:
1) Caffeine – in low to minimal doses, it is clear that caffeine is safe for pregnant women and their offspring. Caffeine easily crosses into the placenta and thus the baby’s circulation. In utero babies cannot metabolize caffeine well putting them at risk with increasing exposure. The data does not support the same reality for more moderate to high doses. Caffeine is known to raise blood pressure and heart rate in all users in variable numbers based on metabolism capabilities…… plus a literature review and a recipe.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 51

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Literature Review
1) High resting cardiac vagal tone or control, CVC, is associated with more flexible emotional responding to external stressful stimuli. With regard to vagal changes the evidence shows us that stress will decrease CVC . (Balzarotti et. al. 2017)
Being relaxed and not stressed out is always associated with better cellular physiology. CVC is a marker of relaxation and thus emotional control. Whenever you find yourself emotionally dysregulated, there is a good chance that your vagal tone is off. Work to meditate, exercise and relax which will increase CVC and help you cope.
2) Continuing on the same theme….. plus a discussion on maternal neural hormonal rewiring, and a recipe of the week.

Dr. M’s Women and Children First Podcast #61 – Bridget Briggs, M.D. – Hope and Epigenetics Part 3

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This is the third story of hope for us as a species. We have a level of control over our outcome that is baked into our DNA.
Bridget R. Briggs, M.D. and I sit down today to discuss the clinical approach to epigenetics in patients especially women. She is a physician who specializes in Women’s Health. Dr. Briggs received her undergraduate degree from the University of California Los Angeles in Psychobiology. She then completed her medical degree from University of California San Diego School of Medicine before completing her residency in family medicine as well as internship in Obstetrics and gynecology. She has been in practice for 25 years in Southern California. She is the owner of two family medicine practices in California where she specializes in functional medicine and womens health. She is a well known speaker and educator on the topics of epigenetics and methylation in humans.
Her story is personal regarding her deep dive into epigenetics and health based on her family’s history and experiences to date. We take a winding road looking at the clinical applications of epigenetic understandings as laid out by the experts and trailblazers of DNA methylation and phenotypic change in animals and humans. We get into some controversial topics including vaccination, preparation for, avoidance of and much more. The conversation is open, honest and thoughtful. We finish with a hard look at the pregnancy state and how to achieve optimal outcomes for our offspring. It is another story of hope for humanity.
Please enjoy my conversation with Dr. Bridget Briggs,
Dr. M