Newsletter

Dr. M’s SPA Newsletter Volume 14 Issue 50

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“Life forms on our planet have evolved under the strong influence of a daily light/dark cycle. Sunlight being the primary source of energy for photosynthesis, the daily production of photosynthetic biomass has a predictable diurnal rhythm. The daily cyclical production of photosynthesized chemical energy is at the base of the food chain. Daily changes in light and darkness result in diurnal rhythms in other environmental parameters such as temperature and humidity. Such a predictable and robust daily rhythm in food availability and environmental factors has led to the evolution of a ~24 h internal timing mechanism or circadian rhythm to enable organisms to anticipate daily changes and to optimize fitness. Fundamental to this 24 h rhythms is the ability to acquire food when it is available and to store a portion of these resources for utilization during the rest of the day (i.e. the fasting period) without compromising fitness and vitality. The fasting period also serves as a time for standby and repair so that the organism is fit and competent to harvest energy when light (for photosynthetic organisms) or food becomes available. While many non-photosynthetic lifeforms with short lifespan (< a few days) may not derive profound benefit from a circadian timing system, they share fundamental biochemical mechanisms for acquiring and storing food when it is available and then utilizing this stored energy during a quiescent period of fasting for repair, stress resistance and vitality.” (Longo et. al. 2016)

This is the crux of the understanding that we, the homo sapiens on Earth, need to realize that biology trumps any desire that we may have to fight against it. We are and have been moving in the wrong direction for quite some time as it relates to what we were meant to do biologically as children and then adults. Not coordinating activity with the sun is a negative recipe for health. Third shift workers are the canary’s in the coal mine for the risks of working and being awake when the sun is down and sleeping when it is up. This population has some very high risks for metabolic disease based on the data. (Biggi et. al. 2008)

Plus a section on filaggrin genes and skin function.

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 49

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Over the next few weeks, I will be doing a deeper dive into the world of eczema or atopic dermatitis. In the greek language where we derive many of our medical terms, eczema is spelled ἔκζεμα or ékzema which means to bubble up. This weeks podcast guest is Dr. Ana Maria Temple, an expert in eczema. We go all over the place in the pod and it is so worth your time if your child suffers from eczema.

Eczema is a multifactorial skin condition that affects millions worldwide, manifesting as red, itchy rash due to inflamed skin. Its prevalence has been steadily rising, particularly in industrialized nations, which suggests a complex interplay of genetics, environmental factors (epigenetics), and immune dysregulation. As we unpack the root causes of eczema over the coming weeks, an integrative functional medicine approach highlights not only the “what” but the “why” behind this condition—providing opportunities for both prevention and healthier management…..plus a section on Skin pH.

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 48

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Holidays and Connection

The Christmas and winter holiday season is a unique time to sit back reflect on the past year. To behold the timeless beauty of life. The shared time offers us an opportunity to pause and connect with those who matter or should matter most in our lives. I love the bathroom plaque that says at the end of life it won’t matter what you owned or what you knew, but rather the impact you had in a child’s life. Fortunately, for us, the holidays bring a chance to foster authentic human connections. To actually sit in conspiracy together. These moments are more than just traditions, they are essential for our emotional, mental, and even physical health. In the hustle of modern existence, where schedules dominate and technology often mediates relationships, we are losing this skill set, especially for the younger generations, making it more important to stay focused now.

Let us define human connection: Human connection is the act or feeling of being seen, heard, cared for and valued by another person or group. It is a most primary need for humans starting in infancy when a child needs a mother’s touch and milk. It arises from the countless meaningful interactions that foster mutual understanding, trust, empathy, and shared emotional experiences that ultimately lead to a child’s feeling of safety. The critical time period to establish attachment and connection is the first 2 to 3 years of life. Plus a section of literature review and a recipe of the week.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Volume 14 Issue 47

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Sulfurophane and health – It is clear now that SFN stands out as a powerhouse phytochemical with profound effects on human health through the pathway of nurclear factor erythroid related 2 (NRF2). It is found abundantly in cruciferous vegetables such as broccoli, broccolini, kale, and brussels sprouts. SFN is a bioactive compound with impressive clinical potential for preventing chronic disease and optimizing cellular health, especially in oxidant impaired/overloaded states. At its core, SFN is a sulfur-rich molecule derived from glucoraphanin, a glucosinolate precursor. The transformation occurs when the enzyme myrosinase, released during the chopping or chewing of cruciferous vegetables, catalyzes the reaction. Interestingly, this enzymatic activation can also be achieved via gut microbiota when raw vegetables are absent from the diet, emphasizing the remarkable adaptability of our biology to source essential nutrients as needed for survival. (Ali et. al. 2023)

Nrf2 is a master regulator of cellular defense, orchestrating the production of detoxification enzymes, antioxidants, and other cytoprotective proteins. By activating Nrf2, sulforaphane enhances the body’s resilience to oxidative stress, a key contributor to aging, inflammation, and the development of chronic diseases such as cardiovascular disease and diabetes. Studies reveal that sulforaphane also induces Phase II detoxification enzymes, such as glutathione S-transferase, which play a vital role in neutralizing and excreting harmful toxins.

Dr. M’s SPA Newsletter Volume 14 Issue 46

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Lymphatics – Refresher

Lymphatics – a plumbing system that follows the circulatory system throughout the body including the brain where it is called the glymphatics. The function of these passively moving tubes is to transport fats around the body, clear cellular debris returning it to the liver and spleen, move fluid in and out of tissue to maintain fluid balance, transport and help immune cells function. By transporting fats , lymph is involved in vitamin movement to tissues and cells for Vitamins A, D, E, K. These are critical functions of metabolism, immunity and detoxification that when disrupted lead to chronic diseases of aging including edema, hypertension, autoimmunity and cardiovascular disease.

“Traditionally considered a passive route for transport of fluid, immune cells, and lipoproteins, lymphatics are now known to be active players in major physiological and pathophysiological processes. Until recently, lymphatic vessel dysfunction was mainly associated with primary and secondary lymphedema. Unexpectedly, however, lymphatic vascular defects have been uncovered in conditions such as obesity, cardiovas- cular disease, inflammation, hypertension, atherosclerosis, Crohn’s disease, glaucoma and various neurological disorders such as Alzheimer’s disease.” (Oliver et. al. 2021)…and a discussion on chemicals in school food.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 45

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Vaccines

In the coming months, I am going to take a deeper look at vaccines. I am fielding lots of questions in the office about the safety of vaccines. People are scared. Are they wrong? Should they be?

Let me start here: first off, I am solidly pro vaccine. That is not the same as to be in agreement with the current vaccine schedule or that vaccines are without risk. I believe that the vaccine schedule and the risk should be questioned on a rolling basis in perpetuetum. This is the function of medical science. Question dogma always. Look for errors of past thinking and reassess on a continual basis.

I think that on the face of it, the skepticism is well placed as the organizations tasked with our safety have made a mess of being honest during the COVID pandemic vaccine rollout….. plus a literature review.

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 14 Issue 44

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Treatment – sometimes it is just better to watch and wait.

Warts are a common ailment of childhood. Mostly a nuisance, sometimes a hindrance to function when located on the fingers and or areas of high use. There are two major types of wart type skin lesions – typical verrucous warts and molluscum contagiosum.

Google has great molluscum and wart Images

WARTS/MOLLUSCUM – To Treat Or Not To Treat?

Common warts and molluscum contagiosum lesions are benign, but bothersome viral skin lesions that are common in children. We see them all the time in clinic. A common viral wart is caused by the human papillomavirus (HPV). HPV infects the epithelium of the skin, leading to keratinocyte proliferation in the skin’s outer layer. This uncontrolled growth of the keratinocytes results in a thickened rough round lesion that we see. If the immune system fails to fully clear the virus, we see this lesion for months to years. Molluscum, caused by an unknown virus, follows a similar course with a dissimilar appearance. Neither molluscum nor warts have roots despite the myth propagated over the years. Molluscum lesions have a turbid white appearance under the umbilicated skin papule with the virus located within the upper skin layer. They are 1-4 mm in diameter. Viral warts are a little larger usually 3 -10 mm in size. They form a protective cap of dead skin (keratinocyte) cells and invade the deeper skin layer. The protective cap is rough like sand paper. Molluscum lesions peak around ages 2-7 years and for common warts the peak age is 7-15 years…. and more on a literature review.

Dr. M

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