micronutrients

Dr. M’s Women and Children First Podcast #66 – James Greenblatt, M.D. – ADHD

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Attention Deficit and Upstream Personalized Treatments
This week we sit down with Dr. James Greenblatt, a pioneer in the field of integrative medicine/psychiatry. He obtained his MD and completed his psychiatry residency at George Washington University School of Medicine. This training was followed by a fellowship in child and adolescent psychiatry at Johns Hopkins Medical School. He has been studying and educating providers on functional psychiatry for 4 decades. Dr. Greenblatt has served as the Chief Medical Officer at Walden Behavioral Care in Waltham, MA for nearly 20 years, and is an Assistant Clinical Professor of Psychiatry at Tufts University School of Medicine and Dartmouth College Geisel School of Medicine.
His focus is on the scientific evidence for nutritional interventions in psychiatry and mental illness. This is the essence of going upstream to right the wrongs of the biochemical pathways of the brain. He is the author of eight books, including the best-seller, Finally Focused: The Breakthrough Natural Treatment Plan for ADHD. His updated edition of Answers to Anorexia was released in October 2021 and his newest book, Functional & Integrative Medicine for Antidepressant Withdrawal is available now.
Dr. Greenblatt is the founder of Psychiatry Redefined, an educational platform dedicated to the personalized, evidence-based treatment of mental health. Psychiatry Redefined offers continuing online education, CME-approved courses, and webinars, and boasts the most comprehensive and scientifically-based professional fellowship for mental health providers, The Psychiatry Redefined Fellowship in Functional & Integrative Psychiatry.
Please enjoy my conversation with Dr. James Greenblatt.
Dr. M

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Dr. M’s Women and Children First Podcast #59 – Randy Jirtle, Ph. D. – The Imprintome and Hope

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Randy Jirtle, Ph.D.
This week’s guest is Professor Randy Jirtle.
Dr. Randy Jirtle joins the show for the second time today to discuss his new research on the imprintome, the regulatory regions that at the earliest stages of fetal development control our epigentic and thus our genetic outcome. This is the Hope locus.
Time Magazine nominated him for person of the year in 2007 and had this to say about him: “Dr. Jirtle’s pioneering work in epigenetics and genomic imprinting has uncovered a vast territory in which a gene represents less of an inexorable sentence and more of an access point for the environment to modify the genome. His trailblazing discoveries have produced a far more complete and useful understanding of human development and diseases” — Time Magazine. This interview is ground zero for the Women and Children First Podcast as we discuss the underpinnings or mechanisms of disease risk for all humans as it relates to the environmental inputs of our lives that are driving health or disease at both the pregnancy and post natal periods. We look specifically at how maternal nutrition and later chemical exposure directly affected the health of the agouti mouse offspring. This experiment was the first of its kind and paved the way for a complete shift in human disease understanding. For parents, this podcast is really the beginning of everything that I am trying to convey regarding a healthy pregnancy and childhood. Without this interview, the following interviews will be more difficult to understand. The picture becomes very clear once his research is cemented in our minds.
His biography is as follows: Professor of Epigenetics at the Department of Biological Sciences, North Carolina State University, Raleigh, NC, and a Senior Scientist at McArdle Laboratory for Cancer Research at the University of Wisconsin, Madison, WI. He was previously professor of radiation oncology and associate professor of pathology at Duke University, Durham, NC, where he had been a faculty member since 1977. He graduated with a B.S. degree in nuclear engineering in 1970 and a Ph.D. degree in radiation biology in 1976, from the University of Wisconsin-Madison. His awards list is long but the key to Dr. Jirtle is that he is a curious thinker and we are grateful for this.
Please enjoy my conversation with Dr. Randy Jirtle,
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 39

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Maternal Nutrition and the Microbiome – Part I

This was a tricky topic to drill down into one article – so I split it into two. Bear with me on this topic as it is so important in the grander scheme of maternal and child health.
The microbiome by definition: the microorganisms that reside in a particular environment.
Pregnancy is a dynamic event where a woman’s body changes radically, including epigenetically, hormonally, immunologically and physiologically in order to conceive and carry a baby to term. Pregnancy has always been a scientific fascination because of these changes. Now, we add the microbiome to the list, as it is the latest area of research that is shedding light on how pregnancy outcomes are determined.
Part I
This was a tricky topic to drill down into one article – so I split it into two. Bear with me on this topic as it is so important in the grander scheme of maternal and child health. The microbiome by definition: the microorganisms that reside in a particular environment. Pregnancy is a dynamic event where a woman’s body changes radically, including epigenetically, hormonally, immunologically and physiologically in order to conceive and carry a baby to term. Pregnancy has always been a scientific fascination because of these changes. Now, we add the microbiome to the list, as it is the latest area of research that is shedding light on how pregnancy outcomes are determined…… also two sections on covid vaccines and disease…
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 36

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Literature Review this Week

1) From Cell Host and Microbe – “The microbiomes of cesarean-born infants differ from vaginally delivered infants and are associated with increased disease risks. Vaginal microbiota transfer (VMT) to newborns may reverse C-section-related microbiome disturbances. Here, we evaluated the effect of VMT by exposing newborns to maternal vaginal fluids and assessing neurodevelopment, as well as the fecal microbiota and metabolome. Sixty-eight cesarean-delivered infants were randomly assigned a VMT or saline gauze intervention immediately after delivery in a triple-blind manner…… and much more about the cutting edge science of today. Also a piece on napping followed by the recipe of the week.

Enjoy,

Dr. M

 

 

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 32

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Asthma, Allergies and Nutrition – The Story Part III – THE NUTRITION STUDIES – THE TO DO
There is good quality data on specific parts of a diet or nutritional plan as it relates to asthma. This section will detail these micronutrient and macronutrient benefits and how to implement them in an overall asthma plan. We will start by looking at a list of high quality nutritional interventions and then follow with an expanded view of a few critical players…… and a second section of mothers and death risk perinatally.
To your health,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 31

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THE NUTRITIONAL STUDIES
We know that the foods that we consume affect our intestinal microbiome, our immune system, our metabolism and therefore have a significant effect on inflammation. Is this knowledge translatable to asthma? Let us look specifically at nutrition as it relates to Asthma. Are there specific diet studies available that lead us toward a unified diet for better asthma health? Can we make good recommendations for our patients on a macronutrient basis with fats, carbohydrates and protein ratios and types. Do we have data to support certain micronutrient needs in asthma and how a diet could provide these nutrients? How much can we trust the data?…..
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 24

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Breastfeeding Versus Formula
Science versus Opinion
I read with somewhat of a frustrated feeling a recent article in Scientific American entitled: It’s Okay Not to Breastfeed by Kavin Senapathy. In principle, the reality of this statement is reasonable. Then you read the article as to what makes this reasonable. She states: “Exclusive breastfeeding is not imperative, and the “breast is best” mantra can be harmful to babies and parents, especially among marginalized people.”(K. Senapathy 2023) Again, at first blush this may seem reasonable. Let’s dig into the science and the truth of breast versus cow milk based formula for optimal health for a child. Does formula in all of its forms work for infant nutrition in order to grow and survive in a reasonable way? The answer is a resounding yes, however, this does not tell the whole story, far from it…..
Enjoy,
Dr. M

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