Vaccines

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 50

Literature Review
1) Pericytes are critical cells that sit around the tiny blood vessels called capillaries of the body especially in the brain. They are involved in regulating blood vessel activity. They communicate directly with the endothelial cells making them super important in the activity of the blood vessel and metabolism at the local tissue interface. From the journal Cell Death and Disease we see: “Crosstalk mechanisms….And some other discussions on Cancer detection at physicals as well as the recipe of the week.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 49

Respiratory Syncytial Virus
RSV is a 150 nanometer RNA virus that comes from a human orthopneumovirus that circulates in the winter primarily. Young children and infants infected with RSV mostly have upper respiratory tract symptoms where a subset develop lower respiratory tract disease known as bronchiolitis with the primary infection. It is the most common reason for hospitalization in infants between 0 and 6 months of age. Bronchiolitis appears as a wheezy, cough centric illness that rarely may progress to increased respiratory effort noted by wheezing, rales (lung crackles – sounds like stepping on leaves), chest wall rib retractions, grunting, fast breathing, nasal flaring and eventually respiratory hypoxia. If it persists, the event can rarely lead to respiratory collapse and death. Annually, 150 children under 5 years of age die from RSV in the US. Most of these children are premature births and have cardiopulmonary disease issues. Term healthy children rarely succumb to RSV in a serious way. A recent study of German infants and children hospitalized with RSV identified these risk factors: age <6 months, birth at 28–37 weeks gestational age, congenital defects, perinatal respiratory and cardiovascular disorders, and various other comorbidities as significant risk factors for ICU admission and death. ( Cai et. al. 2020) plus a mini lit review and a discussion on thanksgiving.
Enjoy
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 41

Literature Review:

  1. Over the past 15 years we have noted a connection between the intestinal microbiome and allergic/autoimmune disease activity in humans. This study continues to pull on this thread of knowledge. We see a direct correlation between a dysbiotic microbiome and human disease risk as young as 5 years of age. The upstream targets remain the same. Healthy food, avoidance of chemicals, consistent daily movement, exposure to normal macrobes and microbes, chronic stress mitigation, vaginal deliveries, breast feeding, avoidance of antibiotics/antacids and more…..Then Section II with – Are we addicted to food? and the recipe of the week.

Enjoy,

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 9

Coronavirus Update 81 plus other stuff
We continue to have a highly infectious Omicron endemic national state with new strain XBB.1.5 accounting for 75% of our cases now with absolutely no signs of worsening disease severity or morbidity. Having had a previous Omicron natural infection is beneficial towards preventing moderate to severe disease from current circulating Omicron strains, but not helping against getting mild infection at all. This week we look at the residual data that is of interest. It is thinning out for me. We also look at men’s health and the micronutrient iodine.
Enjoy,
Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 13 Issue 5

 

Covid update #79 – This week we do a literature review looking at Covid and the post illness effects on lipid metabolism, chemical clearance and general long term health. We look at the effects of different mask types. We have a lifestyle Covid illness mitigation strategy moving forward. We finish with a look at liver and a recipe using liver as a main ingredient.   Enjoy, Dr. M

Dr. M’s Women and Children First Podcast #39 Paul Offit, MD – Latest Information of Vaccines for Covid and Children

Dr. Paul A. Offit is Director of the Vaccine Education Center and professor of pediatrics in the Division of Infectious Diseases at Children’s Hospital of Philadelphia. He is the Maurice R. Hilleman Professor of Vaccinology at the Perelman School of Medicine at the University of Pennsylvania.

Dr. Offit is an internationally recognized expert in the fields of virology and immunology, and was a member of the Advisory Committee on Immunization Practices to the Centers for Disease Control and Prevention. He is a member of the Food and Drug Administration Vaccines and Related Biological Products Advisory Committee, a member of the Institute of Medicine and co-editor of the foremost vaccine text, Vaccines.

He is a scientist, a skeptic, a thinker and an individual deeply passionate about children’s health.

This week we sit down again to discuss the latest with Covid, vaccines and children’s health as new data has prompted a new discussion.

I hope that you enjoy my latest conversation with Dr. Offit,

 

Dr. M

Dr. M’s SPA Newsletter Audiocast Volume 12 Issue 47

Covid Newsletter #74. Why are we seeing massive waves of RSV and Influenza A right now? These viruses normally circulate in the winter only. The answer is nuanced, but likely primarily because of the pandemics social distancing and hygiene activity. During the 2020-2022 cycle of Covid fear and mitigation of viral risk, most of us avoided the normal trappings of viral spread. We masked avoiding the viral droplet portal of entry most commonly used. We kept our children semi isolated from other children where most year to year viral transmission events occur. We practiced enhanced hand washing and sanitizing reducing natural viral spread through contact. In essence we stopped the normal propagation of respiratory virus for 2 years. A whole cycle of children between 0 and 2 years old are RSV and flu immune naive leading to a perfect host pool for spread. The 2 to 18 year olds have had a long pause in exposure reducing circulating virus specific antibodies to negligible levels leading to stronger infections and more spread. Anyone who has a child in college (me) has seen infection after infection pound these students this fall. It seems like they are always dealing with a viral illness. Immunity country wide will return in the coming year to these viral illnesses reverting to the old reality of winter predominance.
Quick Covid Hits and other musings –
Enjoy,
Dr. M

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